ocular lesions are a common manifestation of toxoplasmosis in cats. in this survey, 10 healthy syrianmice were infected through intraperitoneal inoculation of bradyzoites of toxoplasma gondii (tehran strain).mice were killed 30 days after inoculation and the suspension of their brains was prepared, after confirmationof the infection. seven kittens were fed with the infected mice brain suspensio...

background: soil structure is mainly composed of sand, silt, clay, and organic materials. organisms can live in the soil. the large number of stray cats in the cities of iran is a major environmental and health problem. toxoplasma oocysts are shed with the feces of cats, so soil is known as a potential source of transmission of toxoplasmosis. the aim of this study was to determine the soil cont...

objective(s):there are supportive evidences about the possible role of latent toxoplasma. gondii infections on the behavior and neurologic functions, such as increased dopamine levels in the brain. the aim of this study was to examine anti-toxoplasma activity of aripiprazole that is an atypical anti-psychotic drug in mice. materials and methods: mice were randomly divided into four groups, incl...

QUESTION One of my female patients was tested for Toxoplasma and found positive for immunoglobulin G (IgG). She is planning to get pregnant soon. What are the risks for her and her baby? ANSWER Up to 25% of Canadians are IgG-positive for Toxoplasma due to past exposure. Immunoglobulin M (IgM) titres indicate current infection. Toxoplasma gondii is an obligate intracellular protozoan that has ...

Resistance to infection with Toxoplasma gondii was studied in mice lacking CD4 expression. Such mice developed more brain cysts and survived for a shorter time than did wild-type controls after peroral infection with ME49 cysts. After immunization with the ts-4 strain of T. gondii, CD4-deficient mice exhibited impaired resistance to a challenge infection with virulent RH tachyzoites. Thus, defi...

Human platelets, in the absence of antibody, are cytotoxic to tachyzoites of Toxoplasma gondii as determined by vital staining, transmission electron microscopy, and the failure of Toxoplasma to survive and replicate in mice after in vitro interaction of the organisms with platelets. Platelet to T. gondii ratios as low as 1:3 were toxic to the organisms with direct cell-cell contact essential f...

OBJECTIVES To determine the frequency of antibody seropositivity of Toxoplasma gondii  infection in a cancer patient population. We also explored on association of Toxoplasma gondii seropositivity with selected variables. Methods: This is a prospective cross-sectional study conducted at  Prince Faisal bin Bandar cancer center, Qassim, Saudi Arabia, from November 2014 to  March 2015. One hundred...

Background: Toxoplasma gondii, as an important food-borne protozoan parasite, occurs widely in humans and animals including domestic poultry throughout the world. The goal of this survey was to determine prevalence rate of T. gondii in free-ranging chickens sold in Tunis, Tunisia. Methods: In the present study, the prevalence of T. gondii in 40 free-range chickens (Gallus domesticus) marketed ...

PURPOSE To evaluate the susceptibility to toxoplasmosis in pregnant women in the public health service from two cities in the western region of Paraná, Brazil. METHODS Four thousand twenty-two pregnant women were evaluated for anti-Toxoplasma gondii IgG and IgM by ELISA and MEIA. Seronegative pregnant women repeated the serology in the second and third trimester of pregnancy. Neonatal screeni...

About 20-90% of the world's population has had contact with Toxoplasma gondii parasites. The aim of this study was to determine the seroprevalence and risk factors associated with T. gondii infection in the Central Region, Ghana. A community-based cross-sectional study was conducted in three selected communities. Serum samples were tested for the presence of anti-T. gondii IgG and IgM antibodie...