cirrhosis is characterized by marked abnormalities in the cardiovascular system. a hyperdynamic splanchnic and systemic circulation is typical of cirrhotic patients and has been observed in all experimental forms of portal hypertension. the hyperdynamic circulation is most likely initiated by arterial vasodilatation, leading to central hypovolemia, sodium retention, and an increased intravascul...

background: in this study, we used a new computerized analytical method for the measurement of the endothelial function in sequential ultrasound images and compared it with histological studies, using the abdominal aorta in normal and atherosclerotic rabbits. methods: six rabbits received a standard rabbit chow as the normal group and the other 6 rabbits were fed a high cholesterol diet for fou...

background: to assess the endothelial function via noninvasive method, in pregnant women with preeclampsia compared to normotensive pregnant women. materials and methods: brachial artery diameter was measured via ultrasound, in 28 women with preeclampcia in case group and normotensive pregnant women in control group, at rest, after inflation of sphygmomanometer cuff up to 250-300 mmhg, immediat...

The circulatory responses to high equinalgesic doses of morphine are compared with those of pethidin. The decrease in mean arterial blood pressure in case of morphine was 28p.c., with a paralleled and identical de­crease in total peripheral resistance and no negative inotropic effects.  Pethidine decreased blood pressure 54p.c., as a result of peripheral vasodilation of 46p.c. and a sharp drop...

context: normal pregnancy is associated with sodium and water retention, which results in plasma volume expansion prior to placental implantation. the explanation offered for these events is that pregnancy ‘resets’ both volume and osmoreceptors. evidence acquisition: the mechanisms for such an enigmatic ‘resetting’ in pregnancy have not previously been explained. however, recent human pregnancy...

background: autoregulation of blood flow is a marvelous phenomenon balanc- ing blood supply and tissue demand. although many chemically-based explanations for this phenomenon have been proposed and some of them are commonly used today, biomechanical aspects of this phenomenon was neglected. the biomechanical aspect provides insights to us to model vessel diameter changes more precisely and comp...

rhododendron dauricum l. is an ancient chinese traditional herb. the pharmacological effects of r. dauricum extract have been shown in chronic tracheitis. the aim of this study was to investigate the cardiovascular effects of rhododendron dauricum l. flavonoids (rf) on rats and its mechanisms. this study was performed in isolated vascular rings and a rat model of myocardial infarction and isola...

objective(s): angiotensin ⅱ type 1 receptor blockers (arbs) represent one of the widely used antihypertensive agents. in addition to anti-hypertension effect, some arbs also show other molecular effects such as activating peroxisome proliferator-activated receptor-γ and so on. here we studied the effects of telmisartan on the rat isolated mesenteric artery rings pre-contracted by phenylephrine ...