Many investigators have used proteomic methodologies to investigate specific questions in basic biology and medical science. Indeed, many millions of dollars have been spent around the world on the generation of extensive lists of proteins that reside in a particular organelle, cell type, tissue, or body fluid. These lists represent the proteomes of those specific systems. Many studies attempt ...

Minimal residual cancer is defined as “the presence of tumor cells that are not detectable by the current routine diagnostic procedures used for tumor staging in cancer patients after surgical removal of the primary tumor.” Data from European and North American groups have demonstrated the prognostic impact of disseminated tumor cells (DTCs) in the bone marrow of breast cancer patients. Circula...

This paper examines the changing nature of attitudes toward and reports of sexual harassment using data for 1978–94 drawn from the U.S. Merit Systems Protection Board (USMSPB) of the U.S. federal government. The authors find that although unwanted sexual behavior reported by federal government employees changed only slightly in overall incidence over the period, its pattern changed noticeably. ...