نتایج جستجو برای: WG

تعداد نتایج: 3422  

Journal: :Development 2005
Chun Han Dong Yan Tatyana Y Belenkaya Xinhua Lin

Drosophila Wingless (Wg) is the founding member of the Wnt family of secreted proteins. During the wing development, Wg acts as a morphogen whose concentration gradient provides positional cues for wing patterning. The molecular mechanism(s) of Wg gradient formation is not fully understood. Here, we systematically analyzed the roles of glypicans Dally and Dally-like protein (Dlp), the Wg recept...

Journal: :Information Polity 2011
Adegboyega K. Ojo Tomasz Janowski Elsa Estevez

The Whole of Government (WG) approach is increasingly seen as an imperative for delivering coherent and integrated policies, joined up and seamless services, and integrated program management in government. Although no generic WG framework currently exists, there are reported cases of WG initiatives by different governments. Grounded in existing theories, frameworks and cases related to inter-o...

Journal: :Nuclear Physics News 2017

Journal: :MMW - Fortschritte der Medizin 2010

Journal: :Current Biology 2000
Maura Strigini Stephen M. Cohen

BACKGROUND Secreted signaling proteins of the Wingless (Wg)/Wnt, Hedgehog and bone morphogenetic protein (BMP)/Decapentaplegic (Dpp) families function as morphogens to control growth and pattern formation during development. Although these proteins have been shown to act directly on distant cells in the developing limbs of the fruit fly Drosophila, little is known about how ligand gradients for...

2017
Han Gao Fang He Xinhua Lin Yihui Wu

Drosophila Wingless (Wg) is a morphogen that determines cell fate during development. Previous studies have shown that endocytic pathways regulate Wg trafficking and signaling. Here, we showed that loss of vamp7, a gene required for vesicle fusion, dramatically increased Wg levels and decreased Wg signaling. Interestingly, we found that levels of Dally-like (Dlp), a glypican that can interact w...

Journal: :The Journal of Cell Biology 2006
Elaine S. Seto Hugo J. Bellen

The Wnt-Wingless (Wg) pathway regulates development through precisely controlled signaling. In this study, we show that intracellular trafficking regulates Wg signaling levels. In Drosophila melanogaster cells stimulated with Wg media, dynamin or Rab5 knockdown causes reduced Super8XTOPflash activity, suggesting that internalization and endosomal transport facilitate Wg signaling. In the wing, ...

Journal: :Development 1996
K M Bhat

The Drosophila signaling molecule Wingless (Wg) plays crucial roles in cell-cell communications during development. In the developing nervous system, a previous study has shown that Wg acts non-autonomously to specify the fate of a specific neuronal precursor, NB4-2 (Q. Chu-LaGraff and C. Q. Doe (1993) Science 261, 1594-1597). The lack of autocrine specification of NB4-2 in Wg-expressing cells ...

Journal: :The British journal of nutrition 2010
Iain A Brownlee Carmel Moore Mark Chatfield David P Richardson Peter Ashby Sharron A Kuznesof Susan A Jebb Chris J Seal

Recommendations for whole-grain (WG) intake are based on observational studies showing that higher WG consumption is associated with reduced CVD risk. No large-scale, randomised, controlled dietary intervention studies have investigated the effects on CVD risk markers of substituting WG in place of refined grains in the diets of non-WG consumers. A total of 316 participants (aged 18-65 years; B...

Journal: :IEEE Trans. Computers 2015
Hayssam El-Razouk Arash Reyhani-Masoleh Guang Gong

The WG stream ciphers are based on the WG (Welch-Gong) transformation and possess proved randomness properties. In this paper we propose nine new hardware designs for the two classes of WG(29, 11) and WG-16. For each class, we design and implement three versions of standard, pipelined and serial. For the first time, we use the polynomial basis (PB) representation to design and implement the WG(...

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