The work desires: i) to determine the optimum level of batch size in bottleneck facility and ii) to analyze the effect of common components on work-in-process (WIP) level and cycle time in a multistage production system under uncertainties. The uncertainty is created by machine breakdown and quality variation. Few simulation models are developed based on a live case from a company. The models a...

Sequence recognition performance is often summarised first in terms of the number of hits (H), substitutions (S), deletions (D) and insertions (I), and then as a single statistic by the “word error rate” WER = 100(S+D+I)/(H+S+D). While in common use, WER has two disadvantages as a performance measure. One is that it has no upper bound, so it doesn’t tell you how good a system is, only that one ...

Pull systems focusing on throughput time control and applicable in situations with high variety and customization are scarce. This paper compares pull systems that can cope with such situations: POLCA and CONWIP. Both systems constrain the maximum amount of work in progress (WIP) within a loop, but their effectiveness in terms of reducing total throughput time is questioned. They mainly differ ...

The trend in Printed Circuit Board Assembly (PCBA) technology is towards higher complexity. Many boards have significantly more components and solder joints today than just a few years ago. More components and more solder joints means more defect opportunities and lower yields. A higher number of components typically means higher cost for each PCBA, resulting in higher WIP cost (work in process...

In a just-in-time (JIT) system, kanban number and size represent the inventory level of work-in-process (WIP) or purchasing parts. It is an important issue to determine the feasible kanban number and size. In this research, an integrated multiple-objective genetic algorithm (MOGA) based system is developed to determine the Pareto-optimal kanban number and size, and is applied in a JIT-oriented ...

Phagocytosis is a vital first-line host defense mechanism against infection involving the ingestion and digestion of foreign materials such as bacteria by specialized cells, phagocytes. For phagocytes to ingest the foreign materials, they form an actin-based membrane structure called phagocytic cup at the plasma membranes. Formation of the phagocytic cup is impaired in phagocytes from patients ...

OBJECTIVES This paper tried to review a recent research trend for the environmental exposure of engineered nanomaterials (ENMs) and its removal efficiency in the nanowaste treatment plants. METHODS The studies on the predicted environmental concentrations (PEC) of ENMs obtained by exposure modeling and treatment (or removal) efficiency in nanowaste treatment facilities, such as wastewater tre...

Aggregate production planning for highly re–entrant production processes is typically generated by finding optimal release rates based on clearing function models. For production processes with very long cycle times, like in semiconductor production, dispatch policies are used to cover short term fluctuations. We extend the concept of a clearing function to allow control over both, the release ...

The role of WASP-interacting protein (WIP) in the process of F-actin assembly during chemotaxis of Dictyostelium was examined. Mutations of the WH1 domain of WASP led to a reduction in binding to WIPa, a newly identified homolog of mammalian WIP, a reduction of F-actin polymerization at the leading edge, and a reduction in chemotactic efficiency. WIPa localizes to sites of new pseudopod protrus...

To meet competitive market for the electronics consumer products, the integrated circuit is process at the semiconductor fabrication factory which is the most complex and challenging areas in manufacturing. This is due to semiconductor manufacturers will require to process 300 to 1000 steps depends on products, 60,000 WIP and 400 pieces equipment for typical 200mm wafer size technology. Due to ...