ZO-1, ZO-2, and ZO-3, which contain three PDZ domains (PDZ1 to -3), are concentrated at tight junctions (TJs) in epithelial cells. TJ strands are mainly composed of two distinct types of four-transmembrane proteins, occludin, and claudins, between which occludin was reported to directly bind to ZO-1/ZO-2/ZO-3. However, in occludin-deficient intestinal epithelial cells, ZO-1/ZO-2/ZO-3 were still...

enhancement of antioxidant capacity of plants by natural antioxidants obtained from medicinal plants can be a simple way to produce stress tolerant plants. zataria multiflora essential oil (zo) is one of the useful antioxidants with potent antioxidant activity. zo is insoluble in water and can be degraded by light, oxygen, and high temperature. incorporation of zo into poly vinyl alcohol (pva) ...

An adsorbent ZO (oxidized ZIF-8-derived carbon) was prepared on the carbon (ZC) by modified Hummer’s method. The removal rate and adsorption amount of Pb2+ were measured different molar ratios 2-Hmim to 2, 2′-bipyridine in ZO, including 1:1 (1:1 ZO) 1:2 (1:2 ZO). experiments show that best condition adsorb solution for is an dosage 20 mg, time 16 h, initial Pb2+concentration 15 mg/L, pH = 3; 18...

Defining how the molecular constituents of the tight junction interact is a prerequisite to understanding tight junction physiology. We utilized in vitro binding assays with purified recombinant proteins and immunoprecipitation analyses to define interactions between ZO-1, ZO-2, ZO-3, occludin, and the actin cytoskeleton. Actin cosedimentation studies showed that ZO-2, ZO-3, and occludin all in...

ZO-1, ZO-2, and ZO-3 are closely related scaffolding proteins that link tight junction (TJ) transmembrane proteins such as claudins, junctional adhesion molecules, and occludin to the actin cytoskeleton. Even though the zonula occludens (ZO) proteins are among the first TJ proteins to have been identified and have undergone extensive biochemical analysis, little is known about the physiological...

Introduction: Effect of zinc oxide-eugenol (ZO-E) on bond strength of composite is equivocal. The aim of the present study was to determine if ZO-E affects shear bond strength. Methods: For the purposes of the study, extracted human molar teeth were ground so thatcomposite rods could be bonded to dentine. In group 1, dentine was not exposed to ZO-E. In group 2,...