An extremely sensitive pulse polarographic method for the determination of zinc dimethyldithiocarbamate (an agricultural fungicide) and zinc di-n-pentyldithiocarbamate (a petroleum additive), has been developed based on the reaction of their dithiocarbamate moiety with copper(II) perchlorate in acetonitrile medium. Well defined diffusion-controlled peaks are observed at –140 mV and –130 mV (vs ...

The X-ray structural chemistry of zinc and cadmium 1,1-dithiolates (for example, xanthate, dithiophosphate and dithiocarbamate) with potentially bridging bipyridyl-type ligands (for example, 4,4′-bipyridine) is reviewed. For zinc, the xanthates and dithiophosphates uniformly form one-dimensional coordination polymers, whereas the zinc dithiocarbamates are always zero-dimensional, reflecting the...

The oxidation and degradation of hydrocarbons at high temperature and pressure in the presence of oxygen is one of the common oil product problems. There are many antioxidants to prevent or inhibit oxidation processes; molybdenum and zinc dithiocarbamates are known as powerful antioxidants. In this paper, the oxidation inhibition time of cumene has been investigated using zinc and molybdenum di...

Thirty clinical isolates of Candida albicans and 10 other Candida species were tested for susceptibility to 6 substituted dithiocarbamates and one dimercaptosuccinate. Dimethyldithiocarbamate, sodium pyrrolidine dithiocarbamate, and sodium diethyldithiocarbamate showed dose-dependent antifungal activity which was par­ tially reversed by the addition of zinc, copper, or iron sulfate with greates...

Some pesticide chemicals are based on inorganic elements such as sulfur, copper (i.e. copper sulfate ‘Bordeaux mixture’, copper hydroxide, and copper oxychloride), and arsenic salts (i.e. lead arsenate, calcium arsenate, sodium arsenite), or they contain an inorganic element in their chemical structure such as the organometallic pesticides based on manganese dithiocarbamate (maneb), manganese a...

Ubiquitin activating enzyme E1 plays a pivotal role in ubiquitin based protein signaling through regulating the initiating step of the cascade. Previous studies demonstrated that E1 is inhibited by covalent modification of reactive cysteines contained within the ubiquitin-binding groove and by conditions that increase oxidative stress and deplete cellular antioxidants. In this study, we determi...

A method was developed for the determination of zinc(II) dimethyldithiocarbamate by converting it into the copper(II) dithiocarbamate complex, which is then extracted into molten naphthalene. The absorbance is measured at 430 nm versus a reagent blank. Beer's law is obeyed for concentrations of 0.63 x 10(-3) to 17.2 x 10(-3) g/L in the final solution. The method is sensitive and was applied to ...

Respiratory syncytial virus (RSV) is the major cause for respiratory tract disease in infants and young children. Currently, no licensed vaccine or a selective antiviral drug against RSV infections are available. Here, we describe a structure-based drug design approach that led to the synthesis of a novel series of zinc-ejecting compounds active against RSV replication. 30 compounds, sharing a ...

The influence of deposition temperatures on the structural, elemental, optical and electrical properties was investigated. Rutherford backscattering (RBS) scanning electron microscopy (SEM) were used to measure elemental morphological films. RBS confirms that stoichiometry controlled by with a thickness ranged between 51.00 63.00 nm. SEM data deposited films show different morphologies several ...

Zinc released from excited glutamatergic neurons accelerates amyloid beta (Abeta) aggregation, underscoring the therapeutic potential of zinc chelation for the treatment of Alzheimer's disease (AD). Zinc can also alter Abeta concentration by affecting its degradation. In order to elucidate the possible role of zinc influx in secretase-processed Abeta production, SH-SY5Y cells stably expressing ...