Bovine beta casein A1 is one of the most common variants in dairy cattle breeds; it is considered a risk factor in milk intolerance and in other important human diseases, because of the bioactive peptide beta casomorphin-7 (BCM7) produced by raw or processed A1-milk, but not by A2-milk, during digestion. The aim of this study was to perform a cheap and rapid method to investigate beta casein po...

The selective block of N-type Ca channels by v-conotoxins has been a hallmark of these channels, critical in delineating their biological roles and molecular characteristics. Here we report that the v-conotoxin-channel interaction depends strongly on channel gating. N-type channels (a1B, a2, and b1) expressed in Xenopus oocytes were blocked with a variety of v-conotoxins, including v-CTx-GVIA, ...

[1] The behavior of the coupled carbon cycle and physical climate system in a global warming scenario is studied using an Earth system model including the atmosphere, land, ocean, and the carbon cycle embedded in these components. A fully coupled carbon-climate simulation and several sensitivity runs were conducted for the period of 1860–2100 with prescribed IPCC-SRES-A1B emission scenario. Res...

Climate change is expected to influence spatial and temporal distributions of fish stocks. The aim of this paper is to compare climate change impact on a fishery with other factors impacting the performance of fishing fleets. The fishery in question is the Northeast Arctic cod fishery, a well-documented fishery where data on spatial and temporal distributions are available. A cellular automata ...

We simulate pH-dependent growth of cyanobacteria with an ecosystem model for the central Baltic Sea. Four model components-a life cycle model of cyanobacteria, a biogeochemical model, a carbonate chemistry model and a water column model-are coupled via the framework for aquatic biogeochemical models. The coupled model is forced by the output of a regional climate model, based on the A1B emissio...

Winter storm-track activity over the Northern Hemisphere and its changes in a greenhouse gas scenario (the Special Report on Emission Scenarios A1B forcing) are computed from an ensemble of 23 single runs from 16 coupled global climate models (CGCMs). All models reproduce the general structures of the observed climatological storm-track pattern under present-day forcing conditions. Ensemble mea...

Leishmaniasis is a life-threatening disease caused by protozoan parasites of the genus Leishmania and is transmitted by the bite of several species of sand fly (subfamily Phlebotominae). Global climate change has the potential to alter the distribution of these insect vectors. Here I use maximum entropy (maxent) ecological niche modeling (ENM) and the Intergovernmental Panel on Climate Change(I...

In the future, the Baltic Sea ecosystem will be impacted both by climate change and by riverine and atmospheric nutrient inputs. Multi-model ensemble simulations comprising one IPCC scenario (A1B), two global climate models, two regional climate models, and three Baltic Sea ecosystem models were performed to elucidate the combined effect of climate change and changes in nutrient inputs. This st...

As weather patterns become more volatile and extreme, risks introduced by weather variability will become more critical to agricultural production. The availability of days suitable for field work is driven by soil temperature and moisture, both of which may be altered by climate change. We projected changes in Illinois season length, spring field workability, and summer drought risk under thre...

The potential development of heat-related mortality in the 21th century for Vienna (Austria) was assessed by the use of two regional climate models based on the IPCC emissions scenarios A1B and B1. Heat stress was described with the human-biometeorological index PET (Physiologically Equivalent Temperature). Based on the relation between heat stress and mortality in 1970-2007, we developed two a...