BACKGROUND The recently developed and internally validated Health ABC HF model uses 9 routinely available clinical variables to determine incident heart failure risk. In this study, we sought to externally validate the Health ABC HF model. METHODS AND RESULTS Observed 5-year incidence of heart failure, defined as first hospitalization for new-onset heart failure, was compared with 5-year risk...

FOXP2 shares partially overlapping normal tissue expression and functionality with FOXP1; an established diffuse large B-cell lymphoma (DLBCL) oncogene and marker of poor prognosis. FOXP2 is expressed in the plasma cell malignancy multiple myeloma but has not been studied in DLBCL, where a poor prognosis activated B-cell (ABC)-like subtype display partially blocked plasma cell differentiation. ...

Topological indices are the mathematical tools that correlate the chemical structure with various physical properties, chemical reactivity or biological activity numerically. A topological index is a function having a set of graphs as its domain and a set of real numbers as its range. In QSAR/QSPR study, a prediction about the bioactivity of chemical compounds is made on the basis of physico-ch...

background and aim: multiple sclerosis is a chronic inflammatory disease of demyelinating lesions in the brain, spinal cord and optic nerve. one of the most debilitating symptoms of multiple sclerosis (ms) patients is impaired balance. thus in people with ms, collecting information about the impact of impaired balance on life style and the disability which is being perceived by the patient is e...

Health diagnosis of bearing is essential reduce the breakdowns of rotating machinery. An intelligent method to diagnose the bearing fault using vibration signal is proposed. This paper proposes a binary genetic algorithm (BGA) in feature selection process and discuss about the role of fitness functions in feature selection process by application of different fitness functions in GA process. A v...

Abstract Background Heart failure (HF) has close association with atrial fibrillation (AF). The ESC guideline recommended Atrial Better care (ABC) pathway aims to reduce major cardiovascular adverse outcomes an integrated approach. Optimal medical treatment (OMT) represents the cornerstone in HF management. Purpose To investigate variables affecting OMT and its impact, conjunction ABC adherence...

abc is a simple, yet powerful, textual musical notation. This paper presents abc::dt, a rule-based domain-specific language (Perl embedded), designed to simplify the creation of abc processing tools. Inspired by the Unix philosophy, those tools intend to be simple and compositional in a Unix filters’ way. From abc::dt’s rules we obtain an abc processing tool whose main algorithm follows a tradi...

Research in the design of aspect-oriented programming languages requires a workbench that facilitates easy experimentation with new language features and implementation techniques. In particular, new features for AspectJ have been proposed that require extensions in many dimensions: syntax, type checking and code generation, as well as data flow and control flow analyses. The AspectBench Compil...