The linear mathematical model for springflow suggested by Bear (1979) can simulate springflow for an initial instantaneous recharge. A springflow model has been developed, using the Bear model and Duhamel's approach, which can simulate springflow for time variant recharge. The suggested model can also be used to compute the time variant recharge to the springflow domain from a given springflow ...

An overview is presented of existing groundwater-age data and their implications for assessing rates and timescales of recharge in selected unconfined aquifer systems of the United States. Apparent age distributions in aquifers determined from chlorofluorocarbon, sulfur hexafluoride, tritium/helium-3, and radiocarbonmeasurements from 565 wells in 45 networks were used to calculate groundwater r...

The water crisis is harmful effects on human life. Also one of the most problems in the human society is water resources management. In this study, site selection of most suitable areas for artificial recharge using Boolean model. Criteria used to select the most suitable area for artificial recharge included: infiltration, slope, aquifer thickness, aquifer quality.  The layers were produced an...

The purpose of this study is to propose a theoretical framework based on a balanced scorecard (BSC) for performance measurement in the water desalination supply chain (WDSC). The reason for choosing this context is that the supply chain (SC) of water desalination has received a great amount of attention, due to issues related to the increased need of fresh water for agricultural, industrial and...

The ever increasing demand of water permits the need of alternative water sources for balancing the water supply and demand. Desalination has become a significant alternative water source due to growing demand of water and inadequate conventional water sources in many countries. Desalination is a process of removing excess salts and other dissolved solids from water in order to get clean water ...

Adverse drug reactions (ADRs) are noxious and unexpected effects during normal drug therapy. They have caused significant clinical burden and been responsible for a large portion of new drug development failure. Molecular understanding and in silico evaluation of drug (or candidate) safety in laboratory is thus so desired, and unfortunately has been largely hindered by misuse of ADR terms. The ...

objective(s): acquisition of tnf-α resistance plays role in the onset and growth of malignant tumors. previous studies have demonstrated that mcf-7 cell line and its doxorubicin resistant variant mcf-7/adr are resistant against the cytotoxic effects of tnf-α. in this study, we investigated the role of akt activation in resistance of mcf-7 and mcf-7/adr against tnf-α cytotoxicity. materials and ...

Seawater desalination, the desalination of waters flowing back from hydraulic fracturing processes and brackish water desalination constitute important desalination applications. These have a combined market size in excess of $25 billion per annum and a combined water production rate equivalent to the domestic consumption of over 300 million people. Each application offers its own distinct chal...

Thiopental sodium (TPS) needs to be applied together with adrenalin in order to establish its analgesic effect in general anesthesia. We aimed to investigate the effect of TPS on the claw pain threshold in rats and evaluated its relationship with endogenous adrenalin (ADR), noradrenalin (NDR), and dopamine (DOP) levels. Intact and adrenalectomized rats were used in the experiment. Intact animal...

The purpose of present study was to investigate the effect of dioscin on activity of adriamycin (ADR) in ADR-sensitive (MCF-7) and ADR-resistant (MCF-7/ADR) human breast cancer cells and to clarify the molecular mechanisms involved. Antiproliferation effect of ADR was enhanced by dioscin in MCF-7 and MCF-7/ADR cells. Dioscin significantly inhibited MDR1 mRNA and protein expression and MDR1 prom...