the roots and rhizomes of tanacetum parthenium (l.) schulz. bip. (asteraceae), have been used in iranian traditional medicine under the name of aqhovan, as digestive and stomachic tonic. composition of the essential oil, which was obtained from the root of t. parthenium collected from karaj, was determined by gas chromatography, combined gc/ms and gc/ir. in total, 20 components (92% of essentia...

chronic exposure to lead (pb) affects neural functions in central nervous system (cns) particularly the learning and memory. on the other hand, alteration of calcium level in the cns results in activation of nos. it has been shown that lead enters the neurons through calcium channels and displaces ca2+ from calcium binding proteins such as calmodulin and troponin c thereby affecting calcium-med...

Introduction.-It has been shown earlierl 2 that the synthesis of the isoprenoid, rubber, by a rubber-bearing plant, guayule (Parthenium argentatum), involves acetate as an, intermediate. Not only does the administration of acetate to this plant result in a net increase in the amount of rubber formed, but, in addition, rubber synthesized by plants supplied with doubly C"4-labeled acetate possess...

We measured acetate concentrations in whole blood, serum, and plasma by a modification of a previously described method involving vacuum distillation and gas chromatography. The mean acetate concentration of fresh venous plasma from 27 normal subjects was 51 +/- 5 mumol/L (95% confidence limits ranged from 0 to 103 mumol/L). The acetate concentrations of serum and plasma incubated for 2 h at ei...

OBJECTIVE To evaluate the clinical and hormonal response of topically applied cyproterone acetate, oral cyproterone acetate, and placebo lotion in women with acne. DESIGN Placebo-controlled, randomized study. SETTING Patients were recruited from the Institute of Endocrine Cosmetics, Vienna, Austria. PATIENTS Forty women with acne. INTERVENTIONS Treatment with oral medication consisting ...

Vinyl acetate has been shown to induce nasal lesions in rodents in inhalation bioassays. A physiologically based pharmacokinetic (PBPK) model for vinyl acetate has been used in human risk assessment, but previous in vivo validation was conducted only in rats. Controlled human exposures to vinyl acetate were conducted to provide validation data for the application of the model in humans. Five vo...