Although advances in microsurgery have increased success rates of autologous breast reconstruction, microvascular thrombosis still remains a major concern as a cause of flap failure. At present, no evidence-based guidelines on pharmacological prevention of microvascular thrombosis exist. This study investigates the effect of acetylsalicylic acid on the incidence of microvascular complications i...

It is well-known that acetylsalicylic acid induces gastrointestinal complication. Recently, trefoil factor family has been reported as a mucosal protective factor. We focused on trefoil factor family as one of defensive system for gastrointestinal injuries. The aim of this trial was to evaluate trefoil factor family levels in the serum of healthy subjects with low-dose acetylsalicylic acid. Low...

Objective: To evaluate the effect of chemical stimuli on germination and seedling growth of Caper (Capparis Spinosa) under drought stress. Methods: Factorial experiment in a completely randomized design with four replicates per treatment were performed. First factor of priming include three levels of acetylsalicylic acid (300, 200 and 100 mg/L), gibberellic acid levels (500, 250 and 12...

A total of 100, day-old broiler chickens were randomly divided into 5 groups and kept under elevated temperature (34-36EC) to see the effect of ascorbic acid and acetylsalicylic acid (Sb-Asper-C, a commercial product) on the feed conversion ratio (FCR), immune status and ratio of weight of bursa, thymus and spleen to body weight. Heat stress increased the FCR but decreased the immune response a...

OBJECTIVE To investigate pharmacological interactions of diazepam with non steroidal anti-inflammatory drugs. METHODS Non selective cyclooxygenase enzyme inhibitors (100 mg/kg acetylsalicylic acid, 10 mg/kg inhibitors (100 mg/kg acetylsalicylic acid, 10 mg/kg indomethacin, and 10 mg/kg diclofenac), a selective cyclooxygnase-1 inhibitor (10 mg/kg acetylsalicylic acid), and a selective cyclooxy...

This experimental study of analgesic nephropathy was conducted on rabbit divided into four equal groups (A,B,C,D). Group A served as control. The drugs acetylsalicylic acid (Aspirin) 600 mg/Kg/day and Paracetamol (Acetaminophen) 300 mg/Kg/day alone as well as combination of Acetylsalicylic acid (300 mg/Kg/day) and Paracetamol (150 mg/Kg/day) were administered orally to groups B,C and D respecti...

Although acetylsalicylic acid does not itself induce interferon, acetylsalicylic acid was found to significantly enhance the production of both human alpha interferon and human gamma interferon when added with the appropriate inducers to cultures of human peripheral blood mononuclear cells. The mechanisms associated with this effect were investigated.

A total of 100, day-old broiler chicks were randomly divided into 5 equal groups and kept under elevated temperature (93-97F) to see the effect of ascorbic acid and acetylsalicylic acid on the feed conversion ratio (FCR), immune status and ratio of weight of bursa, thymus and spleen to body weight. Heat stress increased the FCR but decreased the immune response and ratio of bursa, thymus and sp...

In the present research paper, spectrophotometric and chromatographic assay method has been developed for the simultaneous estimation of acetylsalicylic acid and caffeine in bulk and commercial tablets. Acetylsalicylic acid and caffeine showed absorbance maxima at 228 and 275 nm in 0.1N HCl and at 225 and 272 nm in methanol, respectively. These drugs were estimated in formulations by simultaneo...