CD4 antigen levels in sera from asymptomatic intravenous drug users and homosexuals and patients with lymphadenopathy, acquired immunodeficiency syndrome-related complex, or acquired immunodeficiency syndrome were quantitated. Like soluble CD8, CD4 antigen levels were elevated in human immunodeficiency virus-seronegative asymptomatic intravenous drug users and homosexuals, probably reflecting i...

Microsporidia is a common term that has been used to refer to a group of eukaryotic, obligate intracellular protozoan parasites belonging to the phylum Microspora. They are important agricultural parasites, contaminating commercial insects; they are also important by infecting laboratory rodents, rabbits and primates. Ever since the early cases found by Magarino Torres, who reported the presenc...

Aplastic anemia is a bone marrow failure syndrome characterized by peripheral cytopenias and hypocellular bone marrow. Although aplastic anemia is idiopathic in most cases, rheumatic diseases such as systemic lupus erythematosus are recognized as causes of aplastic anemia, with their possible etiological mechanisms being T and B lymphocyte dysfunction and pro-inflammatory cytokines and autoanti...

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Thirty patients with acquired immunodeficiency syndrome were examined by computed tomography. In addition to systemic disease, these patients had a variety of neurologic symptoms and signs. Cerebral toxoplasmosis (six cases) was generally manifested by ring-enhancing lesions with surrounding decreased attenuation. Lymphoma (one case) exhibited a solid enhancing nodule, and progressive multifoca...

Amebiasis is an infection caused by the intestinal protozoan Entamoeba histolytica (E. histolytica). About 90% of infections are asymptomatic, and the remaining 10%of infections produce a spectrum of clinical syndromes ranging from dysentery to abscesses of the liver or other organs. Most asymptomatic carriers harbor nonpathogenic strains {E. dispar) which do not cause invasive disease. Some pa...

A prior diagnosis of HIV increases the risk of lymphoma between 150 to 250- fold, depending on the subtype, as compared with the risk observed in the general population. The advent of highly active anti-retroviral therapy (HAART) has seen a dramatic reduction in AIDS morbidity and a modest reduction in the incidence of opportunistic infections along with a corresponding reduction in Kaposi's sa...