The synthesis of C2-symmetrical bis(β-enamino-pyran-2,4-dione) derivative 3 connected via 1,6-hexylene linker was reported for the first time. X-ray structures and Hirshfeld studies new bis- β-enamino-pyran-2,4-dione along with two structurally related pyran-2,4-dione derivatives 2a,b were discussed. A comparative analysis different intermolecular contacts affecting crystal stability presented....

An electron microscopic technique has been developed to visualize the binding sites of acridine orange to DNA within fixed human leukemic bone marrow cells. This electron microscopic technique provides both higher resolution and increased chemical specificity for discriminating the nuclear binding sites of acridine orange than does the previous fluorescent light microscopy. Acridine orange bind...

The neutrophil count, immature:total neutrophil ratio, C reactive protein assay, nitroblue tetrazolium test and an acridine orange leucocyte cytospin test were evaluated for the diagnosis of neonatal bacteraemia. The acridine orange leucocyte cytospin test gave the highest specificity and positive predictive accuracy, but was less sensitive than the neutrophil count, C reactive protein assay or...

In the crystal structure of the title compound, C(23)H(20)NO(2) (+)·CF(3)SO(3) (-), adjacent cations are linked through a network of C-H⋯π and π-π inter-actions, and neighboring cations and anions via C-H⋯O inter-actions. The acridine and benzene ring systems are oriented at a dihedral angle of 31.4 (1)°. The carboxyl group is twisted at an angle of 66.3 (1)° relative to the acridine skeleton. ...

The proliferation of malware in recent years has motivated the need for tools to detect, analyze, and understand intrusions. Though analysis and detection can be difficult, malware fortunately leaves artifacts of its presence on disk. In this paper, we present Dione, a flexible policy-based disk I/O monitoring and analysis infrastructure that can be used to analyze and understand malware behavi...

In the crystal of the title compound, C(24)H(22)NO(2) (+)·CF(3)SO(3) (-), adjacent cations and anions are connected through C-H⋯O, C-H⋯F and S-O⋯π inter-actions, while neighboring cations via π-π inter-actions [centroid-centroid distance = 3.962 (2) Å]. The acridine and benzene ring systems are oriented at a dihedral angle of 14.6 (1)°. The carboxyl group is twisted at an angle of 87.6 (1)° rel...

The one-pot synthesis of three dragmacidin derivatives is reported. Sarcosine anhydride (4) is brominated and immediately reacted with the corresponding indole to produce the products, namely 3,6-bis(5'-methoxy-3'-indolyl)-1,4-dimethylpiperazine-2,5-dione (1), 3,6-bis(7'-methyl-3'-indolyl)-1,4-dimethylpiperazine-2,5-dione (2) and 3,6-bis-(6'-chloro-3'-indolyl)-1,4-dimethylpiperazine-2,5-dione (...