Experiments were carried out on anesthetized adult New Zealand rabbits. Acute joint inflammation was achieved by intra-articular injection of 2% carrageenan. Radiolabelled microspheres were used to measure the effect of acute inflammation on blood flow in the knee joint and establish whether neural influences on blood vessel caliber were affected. Surgical exposure of the posterior joint "capsu...

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a new pandemic virus, a global concern, and has threatened human health. This virus binds to the Angiotensin-Converting Enzyme 2 (ACE2) that is expressed on different cells, especially on the alveolar cells. So the virus can enter the lung cells and causes respiratory syndromes. In Coronavirus Disease 2019 (COVID-19)  that is cause...

We studied the sensory afferent properties of normal, immobilised and inflamed rat knees by recording the activity of the medial articular nerve (MAN). When the knee was inflamed by kaolin-carrageenan or immobilised for six weeks, MAN activity significantly increased during rest and continuous passive motion (CPM). The maximal discharge rate tended to increase depending on the angular velocity ...

Inflammatory condition is the consequence of defensive mechanism of immune system against viral and bacterial infection, tissue injury, UV radiation, stress and etc. Persistently acute inflammation leads to chronic phase which is characterized by production of pro-inflammatory mediators from T cells. These molecules (e.g. IL-6, TNF-&alpha, IL-1&beta and IL-17) are mostly pleiotropic cytokines i...

Biological therapies such as tumor necrosis factor-alpha inhibitors have advanced the treatment of rheumatoid arthritis, but one-third of patients do not respond to such therapy. Furthermore, these inhibitors are now usually administered in combination with conventional disease-modifying antirheumatic drugs, suggesting they have not achieved their early promise. This study investigates a novel ...

Neuroinflammation is a prominent feature of the response to CNS trauma. It also an important hallmark various neurodegenerative diseases in which inflammation contributes progression pathology. Inflammation can contribute secondary damage and therefore excellent therapeutic target for range neurological conditions. nervous system complex varies its fine details different involves wide variety s...

sunburn damage is a physiological disorder, which reducing pomegranate fruits quality and result to huge loss to the gardeners yearly. in this study, the effects of kaolin on maintaining fruit quality and decreasing sunburn damage of malas-e-torsh-e-saveh pomegranate was investigated. processed kaolin (surround® wp) with 0, 2.5, 5 and 10 % (w/v) was sprayed over the whole canopy and fruits at 4...

A patient is described who had a long history of abuse of kaolin and morphine mixture which ultimately proved fatal.

Multiple risk factors are known to exist that will attack cells at various parts of the body eliciting new inflammation sites hence new inflammatory diseases. Acute inflammation usually takes place first in response to the attack of the risk factor (s). As soon as the risk factor (s) is removed, the acute inflammatory response will stop. Conceivably, acute inflammation does not lead to oxidativ...

Although mandibular third molar has a high risk of infection extending any complications, the influence of diabetes on radiolucency and acute inflammation in pericoronitis remains unclear. The present study was to evaluate whether radiolucency below the crown is related to acute inflammation in mandibular horizontal incompletely impacted third molars and to review the records of 140 men more th...