نتایج جستجو برای: acute kidney injury adipose tissue ischemia

تعداد نتایج: 1734170  

2014
Hazel H. Szeto Shaoyi Liu Yi Soong Alexander V. Birk

Szeto HH, Liu S, Soong Y, Birk AV. Improving mitochondrial bioenergetics under ischemic conditions increases warm ischemia tolerance in the kidney. Am J Physiol Renal Physiol 308: F11–F21, 2015. First published October 22, 2014; doi:10.1152/ajprenal.00366.2014.—Ischemia time during partial nephrectomy is strongly associated with acute and chronic renal injury. ATP depletion during warm ischemia...

Journal: :trauma monthly 0
shokofeh banaei department of physiology, ardabil university of medical sciences, ardabil, ir iran; department of physiology, ardabil university of medical sciences, ardabil, ir iran. tel: +98-4512245526 nasser ahmadiasl drug applied research center, tabriz university of medical sciences, tabriz, ir iran alireza alihemmati department of histology and embryology, tabriz university of medical sciences, tabriz, ir iran

conclusions treatment with epo and mel had a beneficial effect on renal ir injury. the results may also indicate that mel protects against morphological damage better than epo in renal ir injury. results ischemia-reperfusion significantly decreased the observed hb and hct values. the histopathological findings in the ir group confirmed that there was an increase in the hyaline cast and thickeni...

Journal: :trauma monthly 0

background renal ischemia reperfusion (ir) contributes to the development of acute renal failure (arf). oxygen free radicals are considered principal components involved in the pathophysiological tissue alterations observed during renal ir. objective in this study, we compared the effects of melatonin (mel) and erythropoietin (epo), which are known antioxidant and anti-inflammatory agents, in i...

Journal: :Journal of the American Society of Nephrology : JASN 2008
Peter Hill Deepa Shukla Maxine G B Tran Julian Aragones H Terence Cook Peter Carmeliet Patrick H Maxwell

Acute renal failure resulting from hypoperfusion and hypoxia is a significant clinical problem. Hypoxia activates the heterodimeric transcription factor hypoxia inducible factor (HIF), leading to changes in gene expression that promote tissue adaptation and survival. To determine whether HIF may protect the kidney from ischemia-reperfusion injury, we subjected hif1a(+/-) and hif2a(+/-) mice to ...

Journal: :iranian journal of basic medical sciences 0
hadi yousefi tuberculosis & lung research center, tabriz university of medical sciences, tabriz, iran naser ahmadiasl tuberculosis & lung research center, tabriz university of medical sciences, tabriz, iran alireza alihemmati department of anatomy and histology, faculty of medicine, tabriz university of medical sciences, tabriz, iran parisa habibi tuberculosis & lung research center, tabriz university of medical sciences, tabriz, iran

objective(s):acute kidney injury (aki), a syndrome characterized by decreased glomerular filtration, occurs in every 1 of 5 hospitalized patients.  renal ischemia-reperfusion, one of the main causes of aki, is of particular importance in the setting of kidney transplantation. materials and methods: sixty male rats were divided into four groups including control, nephrectomy, sham surgery and re...

Journal: :Brazilian Archives of Biology and Technology 2021

HIGHLIGHTS Ischemia-reperfusion triggers acute kidney injury due to reactive oxygen species. Quercetin is an antioxidant flavonoid that modulate the Rennin-Angiotensin System. prevents tubular cell death, oxidation, and mitochondrial depolarization. interacts with angiotensin AT1 receptor.

Journal: :Photonics 2023

Renal ischemia–reperfusion (IR) is inevitable in partial nephrectomy and kidney transplantation. Acute tubular necrosis (ATN) induced by renal IR causes the loss of functional units kidney, pathologically presenting as nonhomogeneous distribution normal uriniferous tubules usually used to characterize activity. Optical coherence tomography (OCT) has been proven have ability image microstructure...

Journal: :journal of paramedical sciences 0
mehrdad hashemi department of pharmacology and toxicology, pharmaceutical science branch, islamic azad university, tehran, iran

global cerebral ischemia (gci) and reperfusion induced apoptosis that lead to cell injury and death. the bax and bcl-2 are pro-apoptotic and anti-apoptotic genes, respectively. these genes belong to the b-cell lymphoma-2 (bcl-2) family.in this study; we assessed the effect of pentoxifylline drug on bax/bcl2 gene dosage expression changes following   ischemic reperfusion injury in kidney. in thi...

2017
Liuhua Zhou Qun Song Jiangwei Shen Luwei Xu Zheng Xu Ran Wu Yuzheng Ge Jiageng Zhu Jianping Wu Quanliang Dou Ruipeng Jia

Stem cells therapy has been suggested as a promising option for the treatment of acute kidney injury (AKI). This study was performed to compare the abilities of xenogenic transplantation of human adipose stromal vascular fraction (SVF) and adipose-derived mesenchymal stem cells (AdMSCs) to facilitate the recovery of renal function and structure in a rat model of ischemia/reperfusion (IR) induce...

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