نتایج جستجو برای: acute kidney injury adipose tissue ischemia

تعداد نتایج: 1734170  

Journal: :American journal of physiology. Renal physiology 2014
Amany Abdelkader Julie Ho Connie P C Ow Gabriela A Eppel Niwanthi W Rajapakse Markus P Schlaich Roger G Evans

Tissue hypoxia has been demonstrated, in both the renal cortex and medulla, during the acute phase of reperfusion after ischemia induced by occlusion of the aorta upstream from the kidney. However, there are also recent clinical observations indicating relatively well preserved oxygenation in the nonfunctional transplanted kidney. To test whether severe acute kidney injury can occur in the abse...

احقری, پریسا , صداقت, زهرا , محمودی, عاطفه , نجفی, عاطفه , کدخدایی, مهری , گلاب, فرشته ,

Background: Several studies indicate that gender differences exist in tolerance of the kidney to ischemia reperfusion (IR) injury. Recently, postconditioning (POC), induction of brief repetitive periods of IR, has been introduced to reduce the extent of the damage to the kidney. This method was shown to attenuate renal IR injury by modifying oxidative stress and reducing lipid peroxidation. Con...

Journal: :Mediators of Inflammation 2005
Yusuf Kenan Coban Ergul Belge Kurutas Harun Ciralik

Fat necrosis remains a serious complication in reconstructive flaps. In clinical setting, it is well known that fat tissue is more susceptible to ischemic events. We aimed to evaluate early histological and biochemical changes of adipofascial tissue in an experimental model. An epigastric flap model in rats was used to evaluate the effect of ischemia-reperfusion (I-R) injury on adipofascial tis...

The patients with renal diseases, especially end-stage renal disease (ESRD), are at high risk of developing cardiovascular disturbances. Some hormones such as brain natriuretic peptide appear to be important serum biomarkers in predicting cardiac death in ESRD patients. Renal diseases cause inflammation, anemia, uremic toxins, fluid overload, and electrolyte disturbance. Kidney transplantation ...

بنائی گیوی, شکوفه, پازوکی, حمیدرضا, همایونفر, همایون ,

    Background & Aim: Occlusion of organs artery results in ischemia and the opening of occluded artery leads to tissue lesion identified as reperfusion injury(RI). Oxygen-derived free radicals seem to be involved in the reperfusion injury. In this experimental study the effects of 5-aminosalicylic acid(5-ASA), a prescribed drug for ulcerative colitis, was assessed. 5-ASA is a potent scavenger ...

Journal: :anesthesiology and pain medicine 0
rudin domi department of anesthesiology and intensive care medicine, “mother teresa” university hospital center, faculty of medicine, medical university of albania, tirana, albania; department of anesthesiology and intensive care medicine, “mother teresa” university hospital center, faculty of medicine, medical university of albania, tirana, albania. tel: +355-682067003 gentian huti department of anesthesia, american hospital, tirana, albania hektor sula department of anesthesiology and intensive care medicine, “mother teresa” university hospital center, faculty of medicine, medical university of albania, tirana, albania nehat baftiu clinic of anesthesiology and intensive care, university clinic center, faculty of medicine, “hasan prishtina” university, prishtine, kosovo myzafer kaci department of anesthesiology and intensive care medicine, “mother teresa” university hospital center, faculty of medicine, medical university of albania, tirana, albania artan bodeci department of anesthesiology and intensive care medicine, “mother teresa” university hospital center, faculty of medicine, medical university of albania, tirana, albania

conclusions good knowledges for renal function remain a hallmark of daily practice of the anesthesiologist, considering renal function as an important determinant factor in anesthesia practice. context pre-existing renal dysfunction presents specific features that anesthesiologists must deal with. anesthesia and renal function are connected and can interfere with each other. induced hypotension...

Journal: :American journal of physiology. Renal physiology 2017
David R Emlet Nuria Pastor-Soler Allison Marciszyn Xiaoyan Wen Hernando Gomez William H Humphries Seth Morrisroe Jacob K Volpe John A Kellum

We have characterized the expression and secretion of the acute kidney injury (AKI) biomarkers insulin-like growth factor binding protein 7 (IGFBP7) and tissue inhibitor of metalloproteinases-2 (TIMP-2) in human kidney epithelial cells in primary cell culture and tissue. We established cell culture model systems of primary kidney cells of proximal and distal tubule origin and observed that both...

Journal: :nephro-urology monthly 0
heihachi migita department of medical engineering, faculty of health sciences, kyushu university of health and welfare, yoshinomachi, nobeoka, japan; department of medical engineering, faculty of health sciences, kyushu university of health and welfare, yoshinomachi, nobeoka, japan. tel: +81-982235555, fax: +81-9825618 shigenori yoshitake department of medical engineering, faculty of health sciences, kyushu university of health and welfare, yoshinomachi, nobeoka, japan yoshihiro tange department of medical engineering, faculty of health sciences, kyushu university of health and welfare, yoshinomachi, nobeoka, japan narantsog choijookhuu department of anatomy, faculty of medicine, division of histochemistry and cell biology, university of miyazaki, kyotake, miyazaki, japan yoshitaka hishikawa department of anatomy, faculty of medicine, division of histochemistry and cell biology, university of miyazaki, kyotake, miyazaki, japan

results a significant decrease in apoptotic cells and increase in proliferative reaction were observed in the i/r + hbo group compared to the i/r group. conclusions we demonstrated that hbo suppressed apoptosis, which caused inflammation after renal i/r, and promoted tubular cell regeneration. hbo has protective effects against aki caused by renal i/r through the inhibition of apoptosis. materi...

Journal: :Trakya University Journal of Natural Sciences 2022

An ischemia-reperfusion (I/R) injury of small intestine is a serious and common condition that result the blockage superior mesenteric artery (SMA) because significant clinical problems. This study evaluated effect Mesna on systemic induced by ischemia/reperfusion (IR) in also liver, kidney lung as remote organs. Forty Wistar albino rats were randomly divided into four groups: control, ischemia...

2017
Geurt Stokman Lotte Kors Pieter J Bakker Elena Rampanelli Nike Claessen Gwendoline J D Teske Loes Butter Harmen van Andel Marius A van den Bergh Weerman Per W B Larsen Mark C Dessing Coert J Zuurbier Stephen E Girardin Sandrine Florquin Jaklien C Leemans

Mitochondrial dysfunction is the most prominent source of oxidative stress in acute and chronic kidney disease. NLRX1 is a receptor of the innate immune system that is ubiquitously expressed and localized in mitochondria. We investigated whether NLRX1 may act at the interface of metabolism and innate immunity in a model of oxidative stress. Using a chimeric mouse model for renal ischemia-reperf...

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