This is the first attempt to systematically record haematological malignancies in Northern Ireland. The methods are identical to a similar effort in other parts of the UK, except that an independent cross check with a cancer registry source was not possible. In addition problems with the census may create differences. Generally, the rates for the leukaemias are slightly lower than in England an...

BMT: bone marrow transplantation CLL: chronic lymphocytic leukemia EF: eosinophilic folliculitis NHL: non-Hodgkin lymphoma SCT: stem cell transplantation WBC: white blood cell INTRODUCTION Well-recognized variants of eosinophilic folliculitis (EF), also known as eosinophilic pustular folliculitis, include Ofuji disease, infantile EF, and HIV-associated EF, which is considered a defining illness...

Children with neurofibromatosis type 1 (NF1) are predisposed to malignancies such as brain tumors, leukemia, and pheochromocytomas. The aim of this study was to evaluate malignancy in patients with NF1. We studied 120 patients with NF1 in this study. Demographic data from these patients were retrospectively reviewed. We found 20 malignancies in 19 patients in our study. Ten children with NF1 ha...

AIMS To determine cause specific mortality in a cohort of 2266 chemical workers exposed to benzene in various manufacturing processes after 1935. METHODS The cohort has accumulated over 80 000 person-years of observation; about 70% of the workers were followed for more than 30 years since first exposure. RESULTS Mortality from non-malignant diseases of the blood was increased (SMR 2.17, 95%...

Treatment of children with acute lymphoblastic leukaemia (ALL) and non-Hodgkin's lymphoma has become more intensive and more successful in recent years. The first few months from diagnosis are punctuated by repeated admissions to hospital for periods of intensive chemotherapy, and often by readmission for management of the resulting fever and neutropenia. However, over half of the treatment per...

Between 1977 and 1984 the proportion of children with malignant disease in Britain initially referred to specialist paediatric oncology centres increased from 44% to 71%. The percentage varied considerably with type of disease and region of residence. Children with acute non-lymphoblastic leukaemia, non-Hodgkin's lymphoma, Ewing's tumour, rhabdomyosarcoma, and (during 1981-84) osteosarcoma trea...

Out of 557 routine marrow examinations performed in children receiving maintenance therapy, or having completed therapy, for acute lymphoblastic leukaemia or non-Hodgkin's lymphoma, only 9 marrow relapses were found. Out of 14 marrow examinations performed because of haematological or clinical indications of possible relapse, only 3 failed to confirm relapse. It is suggested that routine marrow...

STUDY OBJECTIVE To assess spatial clustering of childhood leukaemias and lymphomas in New Zealand, using a national dataset from a country with no nuclear installations. DESIGN New Zealand Map Grid coordinates, derived from the birth addresses of cases and controls were used in clustering analyses that applied Cuzick and Edwards' method. SETTING The whole of New Zealand. PARTICIPANTS The ...

Chronic lymphocytic leukemia, the most common adult leukemia worldwide, is considered an indolent but incurable non-Hodgkin lymphoma. Leukemia cutis is an uncommon manifestation of chronic lymphocytic leukemia. We present a case of an adult patient who presented with skin lesion of bilateral ears, which led to the diagnosis of chronic lymphocytic leukemia. We also reviewed the cases of auricula...