Background and objectives: Solanum trilobatum plant parts such as berries and flowers are normally used for the treatment of respiratory illnesses. The toxicity profile of the plant and its parts are not clear. Hence, the present study was planned to investigate the toxicological effects of ethanol extract of leaves of S. trilobatum (EEST) using acute and sub-...

dimethoate (organophosphate insecticide) and lambda-cyhalothrin (synthetic pyrithroid) aretwo frequently used pesticides due to their high effectiveness and rapid breakdown into environmentally safeproducts. the aim of this present study was to assess and compare the acute toxicity of dimethoate(rogor30%ec) and lambda-cyhalothrin (5%ec) on labeo rohita (hamilton). acute toxicity bioassay wascar...

background: repeated applications of animal manure as fertilizer are normal agricultural practices in malaysia that may release veterinary antibiotics to environment from treated animals. methods: environmental risk assessment (era) on 5 commonly used antibiotics and one hormone in malaysian broiler farm was calculated using the ratio of measured environmental concentration (mec) and predicted ...

at first, in order to define acute toxicity of diazinon insecticide and butachlor herbicide, acute toxicity tests (lc5096h) were done, based on standard method (1989) o.e.c.d. in static way and for 96 hours. and the amount of acute toxicity (lc5096h) of diazinon and butachlor in 1 to 2 gram vimba vimba persa fry larva was determined to be 0.09 and 0.61 respectively. in order to do histology stu...

background and objectives: salvia chloroleuca rech. f. & allen., is an endemic species growing wildly in north east and center parts of iran but there is no information about its safety. to provide information about the safety of the species, we evaluated its acute and sub chronic toxicity in rats. methods: in acute toxicity study, the aqueous methanol (80%) extract at a single dose of 2000...

Background and objectives: Arctium lappa belonging to the Compositae (Asteraceae) family has been used as a medicinal and nutritional supplement in the world. The fruits, leaves and roots of the plant are well-known for their pharmaceutical effects. Toxicity of the fruit’s extract in female rats was investigated in the present study. Methods: To assess...

in iranian folk medicine, especially in west of the country, the aromatic water of rheum ribes has been used for several purposes such as fever reduction.  despite the widespread use of this plant as food or as a medicinal plant, there is still lack of information on its toxicity profile.                                                                in the present study we aimed to evaluate th...

The REACH Regulation requires information on acute oral toxicity for substances produced or imported in quantities greater than one ton per year. When registering, animal testing should be used as last resort. The standard acute oral toxicity test requires use of animals. Therefore, the European Chemicals Agency examined whether alternative ways exist to generate information on acute oral toxic...