background mesenchymal stem cells (mscs) are ideal candidates for treatment of diseases. amniotic membranes are an inexpensive source of mscs (am-msc) without any donor site morbidity in cell therapy. adipose tissue derived stem cells (ascs) are also suitable cells for cell therapy. there is discrepancy in cd271 expression among mscs from different sources. in this study, the characteristics of...

A key challenge in tissue engineering a heart valve is to reproduce the major tissue structures responsible for native valve function. Here we evaluated human adipose-derived stem cells (ADSCs) as a source of cells for heart valve tissue engineering investigating their ability to synthesize and process collagen and elastin. ADSCs were compared with human bone marrow mesenchymal stem cells (BmMS...

Adipose-derived stem cells are increasingly targeted as an autologous source of multipotent cells in regenerative medicine. Specifically, reconstructive lipotransfer procedures combine freshly harvested adipose tissue with ADSCs to improve vascularization and tissue grafting [1]. Furthermore, ADSCs offer a wide array of potential uses in tissue reengineering and cell therapies including wound h...

Introduction: Human hematopoietic stem cells (hHSCs) have been used for transplantation in hematologic failures. Because the number of hHSCs per cord blood unit is limited, the expansion of these cells is important for clinical application. It has been reported that cytokines and feeder layer provide a perspective to in vitro expansion of hHSCs. In this regard, cord blood CD34+ cells ex...

Patients with chronic obstructive pulmonary disease (COPD) have chronic, irreversible airway inflammation; currently, there is no effective or curative treatment and the main goals of COPD management are to mitigate symptoms and improve patients' quality of life. Stem cell based therapy offers a promising therapeutic approach that has shown potential in diverse degenerative lung diseases. Precl...

Background: Today, stem cells are the best candidates for cell therapy and tissue engineering. Adipose-derived Stem Cells (ADSCs) an essential source of in replacement therapies many diseases. Objectives: This study compared proliferation ADSCs alginate fibrin scaffolds. Methods: were isolated from adipose cultured or scaffolds with a medium containing PRP 10% FBS 10%. Then, viability percentag...

background: the aim of this research was to evaluate the effect of adipose derived stem cells on bone repair in through and through mandibular bone defects of canine. materials and methods: in this prospective comparative study, adipose-derived stem cells were isolated from subcutaneous fat of lateral thoracic area of 4 dogs. the isolated cells were cultured and expanded through 3 passages. the...

Skin wounds cause damage to the body's first layer of protection. This, disclosed a person to further injury. Wounds normally heal in a very orderly and efficient process. However, activation of this efficient process is sometimes lost in pathologic conditions such as diabetes. The objective of the present study was to evaluate the expression of some genes in Adipose Derived Mesenchymal Stem Ce...