Background & Aims: Transforming white adipose tissue to brown adipose tissue is considered a solution to overcome undesirable effects of obesity in human beings. Thus, the aim of this research was to investigate the effect of eight weeks of high intensity interval training (HIIT) on serum amounts of fibroblast growth factor 21 (FGF21) and Irisin in sedentary obese women. Materials & Methods: T...

The purpose of the present study was to investigate the context of lipid metabolism research in physical activity, lipolysis, lipolysis hormone regulation and the fate of lipolysis products in exercise, fatty acid transporters, some genes involved in lipid metabolism, effect of resistance activity on lipolysis, adaptations of adipose tissue due to physical activity, lipoproteins and apoproteins...

ABSTRACT Background: Coherent scattering leads to diffraction effects and especially constructive interferences. Theseinterferences carry some information about the molecular structure of the tissue. As breast cancer isthe most widespread cancer in women, this project evaluated the application of small angleX-ray scattering (SAXS) for differentiation between normal and cancerous breast tissues....

Background Cleft palate (CP) is a common congenital defect. It makes serious difficulties for cleft-affected children. The gold standard of care is autogenous bone grafting which may cause additional problems in donor site along with disappointing results. Tissue engineering is a promising solution for a widespread range of defects and disorders. It is reasonable to utilize this novel technolo...

Whereas the role of adipose tissue in glucose and lipid homeostasis is widely recognized, its role in systemic protein and amino acid metabolism is less well-appreciated. In vitro and ex vivo experiments suggest that adipose tissue can metabolize substantial amounts of branched chain amino acids (BCAAs). However, the role of adipose tissue in regulating BCAA metabolism in vivo is controversial....

Skeletal muscles play an active role in regulating the metabolic homeostasis through their ability for relating to adipose tissue and endocrine hormones. Contraction of the skeletal muscle leads to increased release of several myokines, such as irisin, which is able to interact with the adipose tissue. Physical activity promotes the irisin mechanism by augmenting the peroxisomes (PGC1-α) in the...

The rates of coronary disease have accelerated dramatically amongst South Asians, driven to an important extent by the atherogenic dyslipidemia and type 2 diabetes that have become so common amongst them. These precursors of vascular disease appear at lower absolute amounts of adipose tissue in South Asians than in whites. In this paper, we set out a new hypothesis--the adipose tissue overflow ...

Background: Adipokins are cytokines predominantely or exclusively expressed by adipose tissue that circulate and affect target tissues. Four known adipokines, adiponectin, visfatin/PBEF, omentin and vaspin, all increase tissue sensitivity to insulin, and are thus described as ’beneficial’. In this review such biological actions and potential roles of the adipokines leptin, adiponectin and resis...