Stem cells are undifferentiated self regenerating multi potential cells. There are three types of stem cells categories by the ability to form after cells and correlated with the body’s development process. Totipotent: these stem cells can form an entire organism such as fertilized egg. Ploripotent: ploripotent cells are those that can form any cell in the body but cannot form an entire organ...

conclusions tissue engineering may open a new window in cleft palate reconstruction. stem cells and growth factors play key roles in this field. results we reported a summary of the key-points concerning cleft palate development, the genes involving this defect, current therapeutic strategies, recently novel aspects, and future advances in treatments for easy and fast understanding of the conce...

fluoxetine is a common antidepressant which selectively inhibits serotonin reuptake at synaptic level. some research findings have proposed the effect this drug on neurogenesis, neuronal survival as well as proliferation of the neural progenitor cells. endometrium is a part of uterus which harbors mesenchymal stem cells. this source of stem cells can be differentiated into neural cells which ma...

introduction: mesenchymal stem cells can be isolated from adult tissues, such as the adipose tissue, or other sources. among all these sources, adipose tissue because of easy access, and placenta due to its immunomodulatory properties, in addition to another useful properties, were attracted more attention to themselves. isolation and comparing these two different sources can help us for access...

background: the aim of this study was optimization of the polyfect gene delivery method of pcdna3.1 expression vector transfected with the mouse pdx-1 gene in three different kinds of mesenchymal stem cells and hepa cells as well as comparison of transfection efficiency leading to expression of the mentioned gene in the cell types used. materials and methods: rat bone marrow-derived mesenchymal...

Background: The news regarding the successful treatment of uncured diseases is extremely exciting. Recently, the study of stem cells has been widely considered. Objectives: The stem cells have the potential to be converted to all specialized functional cells. Methods: Advances in cell engineering and genetic reprogramming of the stem cells have contributed to novel approaches that may bring h...

background  the mammary gland in humans is a dynamic organ that undergoes significant developmental changes during pregnancy, lactation, and involution. stem cells derived from human breast milk possess the adult stem cell-like characteristics such as self-renewal, proliferative and differentiate potential. this source of stem cells avoids invasive procedures and the ethical controversy of embr...

understanding the molecular mechanisms in regeneration could help the stem cell therapists to improve the clinical practices and could be considered a major milestone in the translation of stem cell research to clinics. chemokines have been described as one of the most significant singling networks in stem cells homing and regeneration of damaged organs. cxcr4/cxcl12 has been known as a key pla...