Objective: One-year adjuvant trastuzumab therapy increases diseasefree and overall survival in the adjuvant treatment of early HER2positive breast cancer. This study aims to assess the long-term cost-effectiveness of adjuvant trastuzumab treatment in Beijing, Shang-

introduction: breast cancers in the early phase frequently undergo distant metastasis and survival of patients is greatly dependent on distant metastasis. the occurrence of micrometastasis has been suggested to relate with prognostic features of breast cancer, such as lymph node metastasis and the presence of vascular invasion. the aim of this study was to examine the presence of keratin-19 mrn...

foot-and-mouth disease is an important viral disease of cloven-hoofed animals. inactivated whole particle virus vaccines are still widely used in prophylactic vaccination campaigns. the choice of adjuvant is a very important factor in enhancing immune responses and the efficacy of inactivated vaccines. montanide isa 61 vg is a new ready-to-use mineral oil-based adjuvant developed by seppic inc....

A transplantable methylcholanthrene-induced glioma has been carried by subcu taneous transplantation in inbred C57/6 mice and grows rapidly within 3-4 weeks in almost all recipients. Immunization with glioma-adjuvant mixture resulted in inhibi tion or "rejection" of 70 per cent of tumor implants given later, whereas immunization with spleen-adjuvant, brain-adjuvant mixtures, or adjuvant alone r...

A polyethylenimine adjuvant modified by mannose, which may be used in the study of vaccine adjuvant, was prepared this paper. Its structure characterized infrared spectroscopy and its micromorphology observed transmission electron microscopy. series mannose-modified polyvinylimine were according to molar ratio primary amine groups between mannose polyvinylimine, their storage stability at 4°C. ...

introduction: influenza can cause more severe diseases and higher rate of morbidity and mortality in the elderly population. therefore, they should receive influenza vaccine annually. however, the host response to vaccine is less in older individuals. on the other hand, selenium can act as a stimulator of the immune system and cause increased immunity and response to vaccine. this study was car...