We read with great interest the article by Tarvasmäki et al. [1], who observed the relationship between vasopressor/inotrope use and outcome in patients with cardiac shock (CS). Their results indicate that use of adrenaline in CS is associated with increased 90-day mortality and marked worsening of cardiac and renal biomarkers during the first few days. The study underscores the need for random...

‘Anaphylaxis is a clinical emergency, and all healthcare professionals should be familiar with its management’. Few health professionals would disagree with this opening sentence of new guidelines from the European Academy of Allergy and Clinical Immunology (EAACI), which aim to provide evidence-based recommendations for recognition, risk assessment, and management of patients who have experien...

Background The incidence of systemic allergic reactions in the UK continues to rise. Appropriate and timely use of an adrenaline auto-injector is life saving. Anaphylaxis guidelines specify that individuals at high risk carry an adrenaline auto-injector at all times and receive adequate instruction on its use. We examined whether adult patients prescribed an adrenaline auto-injector had been gi...

ABSTRACT. Adrenaline complexes with bivalent ions Mg2+, Ca2+, Sr2+ and Ba2+ in methanol at 60 oC were prepared. The prepared isolated characterized using elemental analyses, conductivity measurements, mid infrared, Raman laser, UV-Vis., 1H–NMR spectra, X-ray powder diffraction, scanning electron microscopy energy-dispersive spectroscopy (EDX). Upon the spectroscopic, stoichiometric reactions in...

Subcutaneous adrenaline and terbutaline have been compared in a double blind study of 20 patients with acute severe asthma presenting to an accident and emergency department. Ten patients received adrenaline 0.5 mg (0.5 ml) and 10 terbutaline 0.5 mg (0.5 ml) subcutaneously. Further treatment with nebulised salbutamol (5 mg), hydrocortisone (200 mg), and aminophylline (0.9 mg/kg/hour) was starte...

To determine if enflurane has different effects on myocardial sensitivity to adrenaline than those previously reported for halothane, we have studied the enflurane-adrenaline interaction in isolated canine trabeculae using doses of adrenaline necessary to produce slow responses (adrenaline threshold for the development of slow responses, ATSR) as an indicator. The preparations were depolarized ...

BACKGROUND Hemoptysis occurs due to either pulmonary diseases or bronchoscopy interventions. The aim of the present study was to compare the efficacy of the endobronchial instillation of adrenaline with that of tranexamic acid. METHODS Fifty patients were randomly selected as 2 double-blinded sample groups (n=25). In these patients, bleeding could not be controlled with cold saline lavage dur...

BACKGROUND Salivary alpha amylase (sAA) and chromogranin A (sCgA) have both been suggested as non-invasive markers for sympathetic nervous system (SNS) activity. A complete cervical spinal cord injury leading to tetraplegia is accompanied with sympathetic dysfunction; the aim of this study was to establish the exercise response of these markers in this in vivo model. METHODS Twenty-six elite ...

Aim: The study aimed to evaluate the knowledge levels of pediatric residents about treatment anaphylaxis and correct application skill adrenaline auto-injector (AAI) determine contribution short-term training this level.
 Material Method: A questionnaire form was distributed basic information treatment. And, all participants were asked demonstrate use AAI using demo devices mannequins. Thi...

OBJECTIVE To evaluate the efficacy of aerosolized adrenaline compared to inhaled beta(2) agonists in the treatment of acute asthma in the emergency setting. DATA SOURCES MEDLINE, EMBASE, CINAHI, and Cochrane databases, review articles, and references of included trials. REVIEW METHODS Published (1966-2005) randomized controlled trials with pulmonary function as primary outcome. RESULTS Si...