BACKGROUND: The presence of aflatoxin M1 (AFM1) andantibiotic residues in milk and milk products is a public healthconcern. Milk and milk powder have the potential forintroducing AFM1 and antibiotic into human diet. In recentyears, milk powder has been used on a large scale in dairyfactories. Consequently, antibiotic residues and aflatoxincontamination control in these products has gained impor...

background: aflatoxin m1 (afm1) as a carcinogenic and toxic compound has considerable significance from public health viewpoint. the aim of this study was to determine the level of afm1 in pasteurized and uht milk in west-azerbaijan province of iran. methods: a total of 360 commercial milk samples including 220 pasteurized milk and 140 ultra-high-temperature (uht) milk were purchased randomly f...

use of raw milk and dairy products containing aflatoxin m1 (afm1) has led to concern inconsumers. the present study determined the afm1 in raw cow's milk in qazvinprovince. in this research, 170 raw cow's milk were collected from dairy farm, dairyfactories, milk collection centers, and milk supply centers in qazvin province during coldseasons in 2013, and all samples were examined for afm1. the...

conclusions afm1 contamination of milk is not a concern in this city. however, dairy cattle feed samples of various livestocks must be regularly checked for aflatoxin and the storage conditions of feeds should be strictly controlled. results afm1 was detected in all milk samples. the mean concentration of afm1 was 11.61 ± 0.72 ng/l with a range of 6.3-23.3 ng/l. none of the samples had levels e...

biodetoxification is considered as one of the method for eliminating of aflatoxins including aflatoxin m1 (afm1). in the present study, the ability of lactobacillus acidophilus (la-5) in reduction of afm1 in a simulated gastric model was studied. in this regard, two levels of bacterial suspension (3×109 and 3×1010 cfu/ml) were used to determine their ability to reduce three concentrations of af...

this study was carried out to detect the presence of aflatoxin m1 (afm1) in 30 uht flavored milk samples in karaj, alborz province of iran. high-performance liquid chromatography (hplc) was applied to analyse afm1 in the samples. result showed that aflatoxin m1 was detected in all the uht flavored milk samples, the concentration of afm1 was ranged from 0.015 to 0.14 µg/kg. also, 10 samples (33....

The association between murine cytochrome P3-450 and hepatic aflatoxin B1-4-hydroxylase, a cytochrome P-450-dependent enzyme which converts aflatoxin B1 (AFB1) to aflatoxin M1 (AFM1), was examined by (a) purification of the cytochrome P-450 which preferentially metabolizes AFB1 to AFM1; (b) isolation of the specific cDNA clone; and (c) correlating induction of transcriptional activation of the ...

Background: Aflatoxin M1 (AFM1) as a carcinogenic and toxic compound has considerable significance from public health viewpoint. The aim of this study was to determine the level of AFM1 in pasteurized and UHT milk in West-Azerbaijan province of Iran. Methods: A total of 360 commercial milk samples including 220 pasteurized milk and 140 ultra-high-temperature (UHT) milk were purchased randoml...

background: the presence of aflatoxin m1 (afm1) andantibiotic residues in milk and milk products is a public healthconcern. milk and milk powder have the potential forintroducing afm1 and antibiotic into human diet. in recentyears, milk powder has been used on a large scale in dairyfactories. consequently, antibiotic residues and aflatoxincontamination control in these products has gained impor...