conclusions the results showed that the elderlies living in daycare centers had better qualities of lives physically and mentally. therefore, to improve their qualities of lives in two general physical and mental domains, items such as providing family communications inside or outside the nursing homes as well as planning to fulfill mental and psychological needs besides physical issues like mo...

objective(s):growing evidence indicates that extract of ginkgo biloba (egb) attenuates hippocampal-dependent memory deficit in aged individuals; however, very little is known about the effect of egb on the structure of hippocampus. therefore we examined the egb-induced morphological changes of the cornu ammonis (ca) region in aged rats. materials and methods: sixteen aged male wistar rats, 24 m...

introduction: d-galactose (d-gal) is well known as an appropriate agent to induced aging effects in the in vivo and in vitro models. in the present study, we selected crocin, the main constituent of crocus sativus l. (saffron), against d-gal cytotoxicity in human neuroblastoma sh-sy5y cells. materials and methods:  cells were pretreated with crocin (25-500 µm) for 24 h and then exposed to d-gal...

objective(s): to investigate the effect of cinnamaldehyde and eugenol on the telomere-dependent senescence of stem cells. in addition, to search the probable targets of mentioned phytochemicals between human telomere interacting proteins (tips) using in silico studies. materials and methods: human adipose derived stem cells (hascs) were studied under treatments with 2.5 µm/ml cinnamaldehyde, 0....

hutchinson-gilford progeria syndrome (hgps) is a rare premature ageing disorder that is characterized by accelerated degenerative changes of the cutaneous, musculoskeletal and cardiovascular systems. mean age at diagnosis is 2.9 years and generally leading to death at approximately 13 years of age due to myocardial infarction or stroke. orthopedic manifestations of hgps are multiple and shoulde...

introduction: the prevalence of chronic diseases increases with age. increased production of reactive oxygen species (ros) involves in the pathogenesis of cardiovascular diseases such as coronary atherosclerosis, hypertension, diabetic vascular complications, and heart failure. the present study aimed to explore the effects of resistance training on plasma hydrogen peroxide level of ageing wome...

conclusions cyclosom and histamine synergistically exert catalepsy in old rats. in light of these data, the combination of the decreased brain level of somatostatin and increased brain level of histamine may be of pathogenic relevance for extrapyramidal signs in pd. results cyclosom (0.2, 1.0, and 5.0 µg) and histamine (1.0 and 10.0 µg) alone were ineffective in both young and old animals. in c...

a low carbon al-killed ti-added steel was produced in mobarakeh steel complex in iran. mechanical properties and microstructural characterizations of steel in the as-cast, hot-rolled, cold-rolled and annealed conditions are presented. dilatometery tests were carried out to measure the finishing and annealing temperatures of steel. it was found that the addition of small amounts of ti increased ...

This study was conducted to evaluate the effect of Purslane hydro alcoholic extract on blood urea nitrogen (BUN), creatinine (Cr) and kidney histopathology of kidney aging model induced by D-galactose in female mice. In this experimental study, 72 female Naval Medical Research Institute (NMRI) mice (30-35 g) were randomly divided into six groups including: control, Purslane, D-galactose, D-gala...

    Background: Successful aging as an umbrella term with a large amount of literature has emerged with a variety of meanings and dimensions in different studies. This article aims at determining what dimensions contribute to constructing the concept of successful aging.    Methods: The method used in this study is an integrative review of published literature related ...