In the first paper of this series (1) a model for microheterogeneity of plasma albumins was presented together with some critical evidence in support of its adoption. According to this model plasma albumin consists of a very large number of similar molecular species. The N-F transition of the protein as observed by electrophoresis, solubility, optical rotatory dispersion, and other methods is a...

The anionic calixarenes para-sulphonatocalix[4]arene and 1,3-di-O-phosphonatocalix[ 4]arene, have been used to cap silver nanoparticles. The binding of these functional particles with regard to various serum albumins (bovine serum albumin, human serum albumin, porcine serum albumin and sheep serum albumin) has been studied by variable temperature fluorescence spectroscopy. The quenching of the ...

After albumin transfusion levels of alkaline phosphatase are raised. These levels were studied in selected groups of patients and in albumin prepared for transfusion using a heat sensitivity test, and by this means the significance of raised levels of alkaline phosphatase may be interpreted correctly.

HREE loci controlling the synthesis of serum proteins in the pig have been Tidentified to date. KRISTJANSSON ( 1960a, b) has identified two alleles controlling the synthesis of transferrins in the pig and has demonstrated (1961) three alleles involved in the synthesis of pig haptoglobins. ASHTON (1960) has described three Yhread protein” phenotypes and on the basis of preliminary mating data ha...

Immune cells induced by bovine serum albumin (BSA) and its methylated derivative (MBSA) have been compared in a cooperative cell transfer system for their content of BSA-specific antibody-forming cell precursors (AFCP, B) and BSA-specific helper (T) cells. When MBSA immune cells were transferred together with hapten-primed cells into recipient mice which were stimulated by a hapten-BSA conjugat...

The role of proteins in cerals resistance against the aphids is still poorly recognized. It was discussed if feeding preferences of these insects are related only to their nutritional demands, or rather to their reaction to the toxic compounds in plant tissues. Nowadays it is accepted that both the nutrients and other chemical factors determine their preferences of host plant. Aphid feeding on ...

We synthesized several para-aminophenyl (pap-) mannose-terminated albumins with varying sugar density (Man7-HSA, Man22-HSA, and Man40-HSA) and compared hepatic uptake with (thio-)mannose-terminated bovine serum albumin (Man-43-AI-BSA) The rate of uptake in isolated perfused rat livers was found to be positively correlated with the sugar density (Man40-HSA = Man22-HSA greater than Man7-HSA great...

A simple strategy for choosing optimal bio-supramolecular mediators from the mammalian serum albumin library is proposed for bimolecular photochirogenic reactions. Thus, the enantiodifferentiating photocyclodimerization of 2-anthracencecarboxylate (AC) was optimized in chemical and optical yields, when mediated by porcine and canine serum albumins, both of which bound two AC molecules in the fi...

The synthesis of a novel PS conjugated with bovine and human serum albumin (BSA and HSA) and a monoclonal antibody anti-CD104 is reported, as well as their biological potential against the human bladder cancer cell line UM-UC-3. No photodynamic effect was detected when the non-conjugated porphyrin was used. Yet, when it was coupled covalently with the mAb anti-CD104, BSA and HSA, the resulting ...

Botulinum toxin for medical use is diluted to very low concentrations (nanograms per milliliter); when it is preserved by lyophilization, considerable loss of activity can occur. In the present study, conditions that gave > 90% recovery of the toxicity after lyophilization of solutions containing 20 to 1,000 mouse 50% lethal doses per ml were found. Toxicity was recovered upon drying 0.1 ml of ...