Mite allergens from the Pyroglyphidae family are the most frequent and potent sources of perennial asthma and rhinitis. Since 1988 molecular knowledge has considerably increased and structures and functions have been determined for most of them. Of the 22 denominated allergens, Der p 1 and Der p 2 are major allergens recognized by more than 80% of lgE from Dpt allergic patients in Europe. Der p...

allergic rhinitis (ar) is a common form of allergic disorder in iran and rest of the world. this study was conducted to investigate the symptoms and paraclinical aspects of this allergy among iranian patients. a total of 206 patients (51.5%: male), with one of the specific symptoms of ar, from march 2005 to march 2007 were enrolled in the study. a written questionnaire was completed for each pa...

background nosocomial fungal infections could arise from independent exposure to airborne spores of filamentous fungi existing in the hospital environment. objectives the present study aimed to determine the mycoflora of indoor and outdoor environments of five major hospitals in khorramabad, iran. materials and methods sampling of air was done from indoor and outdoor environments of wards, surr...

Asthma and allergic diseases cases have risen in recent decades. Plant pollen is considered as the main aeroallergen causing allergic reactions. According to available data, urban residents experience more respiratory allergies than rural residents mainly due to the interaction between chemical air pollutants and pollen grains. This interaction can occur through several mechanisms; chemical pol...

IgE antibodies in house dust mite (HDM) allergy follow a predictable pattern. Half are directed against two dominant allergens and the remainder largely against four midpotency allergens. This hierarchical pattern is not changed by the titre of the IgE response or severity of disease. The structures of these allergens are known and they can be produced as authentic recombinant allergens. There ...

background: asthma and allergic rhinitis are among the most common diseases in the world. objective: the aim of this study was to detect, by skin prick test, aeroallergens in allergic patients in sari, mazandaran in north of iran. methods: this is a prospective study of skin prick test of aeroallergens in asthma, allergic rhinitis and their combination with clinical diagnosis. three hundred and...

fractional exhaled nitric oxide (feno) has been suggested as a non-invasive biomarker of airway inflammation, which is increased in atopic subjects. whether sensitization to particular allergens is a predictive factor for increased feno levels is not yet fully understood. we conducted a retrospective cross-sectional study. from october to december in 2015, the medical documents of 127 mild, ste...

The proteins in the food are the source of common allergic components to certain patients. Current lists of plant endogenous allergens were based on the medical/clinical reports as well as laboratory results. Plant genome sequences made it possible to predict and characterize the genome-wide of putative endogenous allergens in rice (Oryza sativa L.). In this work, we identified and characterize...

BACKGROUND Allergy diagnosis needs to be improved in patients suffering from pollen polysensitization due to the existence of possible confounding factors in this type of patients. OBJECTIVE To evaluate new diagnostic strategies by comparing skin responses to pan-allergens and conventional allergenic extracts with specific IgE (sIgE) to purified allergen molecules. METHODS One thousand thre...

BACKGROUND House dust mite allergens are the most important indoor allergens associated with asthma and rhinitis in Singapore and the tropics. Recent data to suggest that besides the Dermatophagoides spp., the domestic mite Blomia tropicalis (Bt) is also an important source of allergens in these regions. OBJECTIVE To evaluate the degree of allergenic cross-reactivity between Bt and D. pterony...