BACKGROUND This paper reviews the current evidence indicating that comorbid allergic rhinitis may have clinically relevant effects on asthma. DISCUSSION Allergic rhinitis is very common in patients with asthma, with a reported prevalence of up to 100% in those with allergic asthma. While the temporal relation of allergic rhinitis and asthma diagnoses can be variable, the diagnosis of allergic...

Studying associations between sibship characteristics and allergic diseases in detail may contribute clues to their etiology. The authors studied associations between sibship characteristics and risk of self-reported allergic rhinitis and asthma among 31,145 pregnant women participating in a nationwide study in Denmark during 1997-2000. Increasing sibship size was associated with a decreased ri...

the purpose of the present study is to investigate the prevalence of th17 and regulatory t (treg) cells in children with allergic rhinitis (ar) accompanying with bronchial asthma (ba).24 children with ar, 22 children with ba, 18 children with ar accompanying with ba,and 20 healthy controls were recruited. the prevalence of peripheral blood th17 and treg cells were determined by flow cytometry. ...

BACKGROUND A clinically relevant relationship between classic asthma and allergic rhinitis has been reported. However, the possible link between cough variant asthma (CVA) and allergic rhinitis remains unknown. OBJECTIVES To clarify the prevalence and clinical relevance of perennial allergic rhinitis or seasonal allergic rhinitis in CVA patients compared to classic asthma patients. METHODS ...

Objective(s): Allergic Asthma is an inflammatory disease of the lungs that is characterized by increased infiltration of leukocytes into the airways, limiting the respiratory function. Studies suggest that a defective general regulatory system against inflammation could be a significant factor in allergic asthma. It has been shown that Mesenchymal stem cells (MSCs) have a cellular immunosuppres...

this study investigated the association between hsv-1 infection and atopy by comparing seropositivity to hsv-1 in atopic children with asthma and allergic rhinitis and in non-atopic children. totally 249 children randomly selected from the university outpatient pediatric clinics were prospectively enrolled in the study between september 1 and november 30, 2007. serum samples were examined using...

Asthma is a complex chronic inflammatory disease of multifactorial etiology. International guidelines increasingly recognize that a standard "one size fits all" approach is no longer an effective approach to achieve optimal treatment outcomes, and a number of disease phenotypes have been proposed for asthma, which has the potential to guide treatment decisions. Among the many asthma phenotypes,...

Background Asthma and allergic rhinitis have become a growing public health problem. The airflow obstruction, pathophysiological event that frames the bronchial asthma is usually determined by spirometry. Changes in expiratory flow in asthma are well known but there is controversy with these results in allergic rhinitis. The objective of this project is to compare spirometry values of young adu...

To investigate if air pollution and greenness exposure from birth till adulthood affects adult asthma, rhinitis lung function. Methods: We analysed data 3428 participants (mean age 28) in the RHINESSA study Norway Sweden. Individual mean annual residential exposures to nitrogen dioxide (NO2), particulate matter (PM10 PM2.5), black carbon (BC), ozone (O3) (normalized difference vegetation index ...

Background: The prevalence of allergic diseases has risen in the last decades. The objective of this study was to determine the common allergens in children via the skin prick test.Methods: This cross-sectional study recruited 313 allergic children (4 months to 18 years old) referred to the Asthma and Allergy Clinic of Children’s Medical Center in Tehran. A questionnaire containing demographic ...