OBJECTIVE To analyze the roles of chemokines and their receptors in the pathogenesis of allergic rhinitis by observing the complementary DNA (cDNA) expression of the chemokines and their receptors in the nasal mucosa of patients with and without allergic rhinitis, using gene chips. METHODS The total RNAs were isolated from the nasal mucosa of 20 allergic rhinitis patients and purified to mess...

Allergen immunotherapy involves the administration of gradually increasing quantities of specific allergens to patients with IgE-mediated conditions until a dose is reached that is effective in reducing disease severity from natural exposure. In the present study we evaluated a period of six years immunotherapy allergic rhinitis and allergic asthma patients with positive skin prick test of comm...

OBJECTIVE The aim of the present study was to investigate the effect of allergic rhinitis on the success of the operation in chronic otitis surgery by using score for allergic rhinitis (SFAR). MATERIALS AND METHODS In the present study; 121 patients, who underwent type 1 tympanoplasty were examined retrospectively. SFAR of all patients were recorded. The graft success rates of 26 patients wit...

P INTRODUCTION A symposium organized by National Jewish Health and held in Denver, Colorado, on October 8, 2009, investigated the role of intranasal antihistamines for allergic rhinitis. It was titled Rethinking the Treatment of Allergic Rhinitis; the Role of Intranasal Antihistamines: “Me Too Drugs” or a Novel Class? Articles 1 through 4 in this supplement provide detailed information about th...

Allergic rhinitis has been shown to affect 3% to 19% of subjects in various epidemiologic studies of different populations. Eighty percent of those with allergic rhinitis experience symptoms by the age of 20 years, and 40% have symptoms by the age of 6 years. Allergic rhinitis is a substantial burden on both adult and pediatric patients, not only because of the bothersome physical symptoms but ...

Familiarity with the diagnosis and management of allergic rhinitis is important for physicians concerned with the nasal airway. Allergic rhinitis is a common and manageable condition that may cause persistent or intermittent symptoms that vary as to duration and severity. Allergic rhinitis impairs quality of life, sleep, school performance, and productivity on a scale that compares with other c...

This study was a review of the literature on the epidemiological, clinical, diagnostic and therapeutic aspects of allergic rhinitis. Bibliographic searches were based on the information contained within the Medline, Latin American and Caribbean Health Sciences Literature and HighWire databases, covering the last thirty years and using the following search terms: ‘allergic rhinitis’, ‘epidemiolo...

BACKGROUND Th2 cell activation and T regulatory cell (Treg) deficiency are key features of allergy. This applies for asthma and rhinitis. However with a same atopic background, some patients will develop rhinitis and asthma, whereas others will display rhinitis only. Co-receptors are pivotal in determining the type of T cell activation, but their role in allergic asthma and rhinitis has not bee...

© Copyright The Korean Academy of Asthma, Allergy and Clinical Immunology • The Korean Academy of Pediatric Allergy and Respiratory Disease http://e-aair.org The definition of remodeling is “model again or differently, reconstruct.” In the airway, reaction to chronic inflammatory conditions can lead to changes in the structural components of the airway wall, known as airway remodeling. Airway r...

BACKGROUND Allergic rhinitis affects a significant proportion of the European population. Few surveys have investigated this disorder in Greek adults. Our objective was to describe the characteristics of patients with allergic rhinitis in an adult outpatient clinic in Thessaloniki, Greece. METHODS We studied the medical records of adult patients referred to a Clinical Immunology outpatient cl...