Aloe barbadensis Miller (or Aloe vera) has widespread use in health products, and despite numerous reports on the whole plant, little work has been performed on the inner gel, which has been used extensively in these products. This report describes the in vitro susceptibilities of two bacteria to this component.

BACKGROUND Due to increasing resistance to antibiotics and rising incidence of oral diseases, there is a need for alternative treatment modalities to combat oral diseases. The aim of the present study was to access the effect of Aloe vera mouthwash on the dental plaque in the experimental period of 4 days and to compare it with the bench mark control chlorhexidine and placebo (saline water). ...

In this study, three novel maloyl glucans were isolated at temperatures below 15 degrees C from aloe vera gel (Aloe barbadensis Miller). These compounds were characterized using NMR spectroscopy, ESIMS, MALDITOF-MS and capillary electrophoresis. The compounds were characterized as 6-O-(1-L-maloyl)-alpha-,beta-D-Glcp (veracylglucan A), alpha-D-Glcp-(1-->4)-6-O-(1-L-maloyl)-alpha,-beta,-D-Glcp (v...

Aloe vera (Aloe barbadensis) is one of the herbal remedies with a longstanding history for its curative and therapeutic properties for various ailments. Till date more than 75 active components with medicinal value have been identified in Aloe vera and have been suggested to possess synergistic action in alleviating the diseased conditions (Scalbert and Williamson, 2000; Hamman, 2008; Nejatzade...

Diabetes mellitus is a multifunctional disorder in which free radicals may cause oxidative cellular injury and changes in the activity of the antioxidant enzymes. So the objective of the study was to find out the antioxidant properties of Aloe vera. Streptozotocin induced diabetic rats were treated with Aloe vera extract (150 mg and 300 mg/kg) and standard drug Vit C (9 mg/kg) in different grou...

Aloe vera has been used in traditional herbal medicine as an immunomodulatory agent inducing anti-inflammatory effects. However, its role on the IL-1β inflammatory cytokine production has not been studied. IL-1β production is strictly regulated both at transcriptional and posttranslational levels through the activity of Nlrp3 inflammasome. In this study we aimed to determine the effect of Aloe ...

The aim of this study was to determine effects of six weeks endurance training and Aloe Vera supplementation on COX-2 and VEGF levels in mice with breast cancer. For this purpose, 35 rats were randomly divided into 5 groups: control (healthy) and 4 cancer groups: control (cancer only), training, Aloe Vera and Aloe Vera + training. Breast cancer tumors were generated in mice by implantind. The t...

Aloe vera is a medicinal plant with anti-inflammatory, antimicrobial, antidiabetic and immune-boosting properties. In the present study we investigated the inhibitory activities of Aloe vera gel on some cariogenic (Streptococcus mutans), periodontopathic (Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis) and an opportunistic periodontopathogen (Bacteroides fragilis) isolated from...

The purpose of this study was to evaluate the effect of topical administration of Aloe vera on excision wound healing in mice. Mechanical skin lesion were used here to assess the efficacy of Aloe vera applied topically. Macroscopic and microscopic evaluation of skin lesions was performed. Excision wounds were made on the back of albino mice. Albino mice were divided into following groups, as co...

The plant Aloe vera has long been used in medicine, as dietary supplements and for cosmetic purposes. Aloe vera extracts are a rich source of polyphenols, such as aloin and aloe emodin and have shown a wide range of pharmacological properties, including anti-inflammatory and anti-cancer properties. The bioactive component aloe emodin has been reported to induce apoptosis in various cancer cell ...