We investigate the structure of rank-to-rank elementary embeddings at successor rank, working in $\mathrm{ZF}$ set theory without Axiom Choice. Recall that set-theoretic universe is naturally stratified by cumulative hierarchy, whose levels $V\_\alpha$ are defined via iterated application power operation, starting from $V\_0=\emptyset$, setting $V\_{\alpha+1}=\mathcal{P}(V\_\alpha)$, and taking...

Alpha-1- antitrypsin is the most important serine protease inhibitor in serum. This protein has several phenotypes. Some of these phenotypes such as MZ, M, Z, M, S, MS, ZZ,…. Cause a,AT deficiency which leads to damage in many tissues such as liver, lung, kidney. 60 patients and 28 healthy individuals (control group), aged 7-65 years old were studied for a,AT activity and a,AT phenotypes. The c...

Bile acid sulfation was studied in primary hepatocyte cultures. The primary hepatocyte cultures formed glycolithocholate-3-sulfate (GLC-S) when glycolithocholate (GLC) was added to the medium. The relative percentage of GLC-S formation increased when the GLC concentration was increased from 10 microM to 100 microM. GLC-S formation was linear to 60 min. GLC-S secretion into the medium was detect...

In 11 128 apparently healthy 18-year-old men screened for alpha 1-antitrypsin deficiency (AATD) 44 had an alpha 1-antitrypsin (AAT) level of 50% or less of the transferrin reference. In 42 of the 44 the Pi types were: five Pi Z, 10 Pi SZ, three Pi MZ, one presumptive Pi M-, one Pi FM, and 22 Pi M. Probably all Pi Z and most of the Pi SZ subjects were identified. The transferrin reference, howev...

BACKGROUND Previous estimates of the survival times of patients with alpha 1-antitrypsin deficiency have been based on selected patients. METHODS The survival times of 397 patients with severe alpha 1-antitrypsin deficiency identified by pulmonary impairment (index cases) or through family studies (non-index cases) were compared. RESULTS The overall median survival time was 54.5 years with ...

Let $A(G)$ be the adjacency matrix and $D(G)$ diagonal of vertex degrees a simple connected graph $G$. Nikiforov defined $A_{\alpha}(G)$ convex combinations as $A_{\alpha}(G)=\alpha D(G)+(1-\alpha)A(G)$, for $0\leq \alpha\leq 1$. If $ \rho_{1}\geq \rho_{2}\geq \dots \geq \rho_{n}$ are eigenvalues (which we call $\alpha$-adjacency $G$), \alpha $-adjacency energy $G$ is $E^{A_{\alpha}}(G)=\sum_{i...