The Drug Evaluation and Classification (DEC) program is used by police agencies to identify drivers impaired because of drug use and to determine the class(es) of drug causing the impairment. The primary goal of this study was to determine the validity of the DEC evaluation in predicting whether research volunteers were administered alprazolam, d-amphetamine, codeine, or marijuana. A secondary ...

In order to adapt their behavior to different unexpected situations, humans need to be able to monitor their performance and detect and correct errors. Benzodiazepines have long been shown to impair performance in humans, but the performance-related neurophysiological processes targeted by these drugs remain largely unknown. In the present article, we assessed the impact of alprazolam administr...

In the present study, Cu(II) and Co(II) complexes have been prepared by reacting metal Nitrate with the ligand (Alprazolam), which have the general structural composition [(L) M(NO3)2], where M=Cu(II) and Co(II) and L=Alprazolam [8-chloro-1-methyl-6-phenyl-4H-1,2,4-trizolo (4,3-a) (1,4) benzodiazepine].The complexes were characterised on the basis of elemental analysis, molecular weight and IR ...

Alprazolam is most commonly used benzodiazepine in overdose for deliberate self-poisoning. Glutaraldehyde cold sterilization of medical, surgical and dental equipment. Poisoning due to accidental exposure as well self-poisoning common with glutaraldehyde. Self-inflicted or hesitational cuts are associated suicide attempted suicidal gestures their examination an important task forensic expert.

UNLABELLED OBJECTIVE. Anxiety is an important cause of acute blood pressure (BP) elevation. However, the role of anxiolysis in this situation is still controversial. In this study, the relationship of anxiety with BP and the effect of anxiolytic treatment on BP were investigated. METHODS. Emergency department (ED) patients with an initial systolic BP (SBP) ≥ 160 mmHg or diastolic BP (DBP) ≥ 100...

BACKGROUND Panic disorder affects 2-5% of the general population. In Argentina, one million people would be affected with a 91% rate of psychiatric comorbidity. AIM; To compare efficacy parameters between sublingual (ALP-SL) and conventional (ALP-CT) tablets of alprazolam in the treatment of acute phase of panic disorder with and without agoraphobia. SUBJECTS AND METHODS A comparative, multic...

In two different experiments, serotonin (5-HT) and 5-hydroxyindoleacetic acid (5-HIAA) levels were measured in rats, using HPLC with electrochemical detection, in 3 brain regions (hippocampus, cerebral cortex and hypothalamus) after acute i.p. treatment with diazepam (4 mg/kg), alprazolam (1.25 mg/kg) or vehicle. In the first experiment, rats received the acute treatment 30 min before they were...

Background. Zao Ren An Shen capsule (ZRASC) is one of the most widely used Chinese herbal medicine (CHM) in treating insomnia, but its effect on insomnia patients with anxiety remains unclear. We aimed to examine ZRASC combined alprazolam compared those only prescription. Methods. conducted a single-blind, parallel-group, randomized trial involving persons from 2 hospitals China. Participants w...