objectives: this descriptive study was conducted to determine the communicative abstract problem between elders with alzheimer disease and there caregivers. methods & materials: 100 main caregivers were selected by census. data was obtained by a questionnaire with a good validity and reliability. its reliability was measured by internal consistency (de=0.96) and test-retest (d=0.96) methods. da...

A qualidade de vida dos cuidadores idosos portadores demência Alzheimer sofre influência diversos fatores, corroborando para a sobrecarga trabalho, tornando-os mais favoráveis complicações físicas e mentais decorrentes do processo cuidar. Objetivo: Identificar os fatores associados demências Alzheimer. Métodos: Trata-se uma Revisão Integrativa da Literatura, conduzida em seis etapas. Seguiu-se ...

Introdução. A neurodegeneração progressiva e irreversível da doença de Alzheimer é uma das principais formas clínicas doença, ocasionando perda gradual memória, raciocínio, compreensão, linguagem, aprendizagem dificuldade na realização tarefas do dia a dia, entre outros. gerada por esta causada mutações nos genes relacionados à síntese proteínas beta-amiloide Tau em várias regiões cérebro assoc...

objectives: loneliness is a common experience of people, regardless of gender, age, socio economic and cultural experience in the course of its life. the aim of this study was to examine the effectiveness of gestalt group therapy on the loneliness of alzheimer’s caregivers. methods: in an experimental study with a pre-post test design and control group, women participants were selected from alz...

introduction: one of the most common markers in alzheimer’s disease (ad) is amyloid beta (aβ) plaques. anti-inflamm-atory agents including phagocytosis by immune cells, proteolytic enzymes and liver are known to decline the risk of aβ plaques formation. in the previous study we showed that aqueous extract of lavandula angusti-folia (lavender) improved memory deficits in alzheimeric rats. here, ...

alzheimer disease (ad) is a neurodegenerative disorder marked by cognitive and behavioral impairment. amyloid beta (aβ) peptides are involved in ad as the main component of amyloid plaques found in the brain. recent in vivo and in vitro studies have shown that there is a lot of substances that alter aβ pathogenesis of ad. aβ induces toxicity lead to increasing ros. in the other hand, 5-ht6 and ...

conclusions both task-related and resting fmri techniques have the potential to detect early brain dysfunction related to ad. however, the use of fmri in ad populations thus far has been limited to a relatively small number of research groups. results bold fmri is considered to reflect the joined synaptic activity of neurons through mri signal changes because of alterations in blood flow, blood...

Employment or Leadership: Mathieu Pelpel, Innogenetics. Consultant or Advisory Role: A. PerretLiaudet, Alzheimer’s Biomarkers Standardization Initiative (ABSI) consortium (Innogenetics); H. Vanderstichele, Biomarkable. Stock Ownership: None declared. Honoraria: None declared. Research Funding: Région Wallonne and W2002134 and 14531 iPCRq contracts to the members of the “Human HistologyCRPP, Uni...

Cerebrovascular disease and Alzheimer disease are common diseases of aging and frequently coexist in the same brain. Accumulating evidence suggests that the presence of brain infarction, including silent infarction, influences the course of Alzheimer disease. Conversely, there is evidence that -amyloid can impair blood vessel function. Vascular -amyloid deposition, also known as cerebral amyloi...