alzheimer's disease (ad) is a chronic neurodegenerative disease that accounts for 60 to 80 percent of all dementia cases. the exact cause of alzheimer`s disease is still unknown, but recent studies suggest neuro-inflammation as an important part of the pathogenesis of the disease. this brings in mind using non-steroidal anti-inflammatory drugs (nsaid) as treatment or prevention of the dise...

Abstract Alzheimer’s disease (AD) is the most common cause of dementia in elderly people. The prevalence of Alzheimer diseases is increasing in the world due to population aging. Metabolic disease such as diabetes and obesity play important role in Alzheimer disease. Hyperglycemia can play important role in brain damage. It causes cognitive impairments, functional and structural alterations in...

Background: Alzheimer dementia as the most common cause of dementia is a chronic, progressive, irreversible and incurable disease. The second most common cause of dementia after Alzheimer is vascular dementia. One of the systems involved in dementia is the visuospatial system and visual evoked potential (VEP) can be one of the diagnostic methods for this disease. Therefore, the present study ai...

The prevalence of major depression is increased in Alzheimer disease (AD), but currently the basis of this association remains unclear. The present study examined rates of depression in 4 groups of participants with postmortem examination from the Baltimore Longitudinal Study of Aging: (1) cognitively normal controls with no Alzheimer pathology, (2) cognitively normal individuals with Alzheimer...

Bilgisayar destekli cihazların ve sistemlerin sağlık alanında kullanımı oldukça yaygınlaşmıştır. Bu cihaz hastalıkların daha hızlı erken teşhisine katkısı yüksekti. Özellikle Manyetik Rezonans Görüntüleme (MRI), Bilgisayarlı Tomografi (BT) gibi görüntüleme cihazları; teşhisin önemli olduğu hastalıklar özelinde büyük bir rol oynamaktadır. Nörolojik hastalıklarda da MR BT görüntülerinin derin öğr...

BACKGROUND Centralization of specialized health care in Denmark has caused increased geographical distance to health-care providers, which may be a barrier for Alzheimer patients to seek health care. We examined the incidence of Alzheimer diagnosis in Denmark between 2000 and 2009 and investigated the association between patients' distance to Alzheimer clinics and Alzheimer diagnoses. METHODS...

We don’t understand Alzheimer, its origin and disease mechanisms. The absence of disease-modifying treatments for Alzheimer today is due to the amyloid hypothesis, a misguided hypothesis of Alzheimer’s etiology, which has dominated research, drug development, clinical trials 30 years. However, the hypothesis is not dead yet, as exemplified by the recent resurrection of clinical with aducanumab....

A doença de Alzheimer se caracteriza por ser uma neurodegenerativa, com um declínio progressivo funções cognitivas e motoras. Devido a esse quadro irreversível apresentar deterioração progressiva, tem efeitos devastadores nos portadores seus familiares. Este trabalho foi desenvolvido o objetivo analisar na literatura os impactos, desafios as atribuições da enfermagem durante processo cuidar vid...

Alzheimer disease is the most common cause of dementia among the elderly, accounting for ~60-70% of all cases of dementia. The neuropathological hallmarks of Alzheimer disease are senile plaques (mainly containing p-amyloid peptide derived from amyloid precursor protein) and neurofibrillary tangles (containing hyperphosphorylated Tau protein), along with neuronal loss. At present there is no ef...