The multiligand Receptor for Advanced Glycation End products (RAGE) is involved in various pathophysiological processes, including diabetic inflammatory conditions and Alzheimers disease. Full-length RAGE, a cell surface-located type I membrane protein, can proteolytically be converted by metalloproteinases ADAM10 and MMP9 into a soluble RAGE form. Moreover, administration of recombinant solubl...

Alzheimers Disease AD is an acute neuro disease that degenerates the brain cells and thus leads to memory loss progressively. It a fatal mostly affects elderly. steers decline of cognitive biological functions shrinks successively, which in turn known as Atrophy. For accurate diagnosis disease, cutting edge methods like machine learning are essential. Recently, has gained lot attention populari...