This book is divided into four main sections. The first section describes noninvasive measures of cerebral aging, including structural (e.g., volumetric MRI), chemical (e.g., dopamine PET), electrophysiological (e.g., ERPs), and hemodynamic (e.g., fMRI), and discusses how they can be linked to behavioral measures of cognitive aging. The second section reviews evidence for the effects of aging o...

We report a detailed morphological, ultrastructural and immunochemical features of neuronal pathology in a case of Alzheimer's disease. This is probably the first detailed study of an autopsy confirmed case from India. The features noted are similar to the ones described from the West.

Physical exercise advantages have been manifested in several neurodegenerative and/or neuropsychiatric disorders implying that these, largely non-invasive, non-pharmacologic interventions, ought to be examined closely in the Alzheimer’s disease (AD) and other dementias context. Thus, according to the tenets of an increasingly broad consensus, preventative and interventional agents for AD and de...

In cerebrovascular networks, some vertices are more connected to each other than with the rest of vasculature, defining a community structure. Here, we introduce class model networks built by rewiring Random Regular Graphs, which enables reproduction this structure and topological properties networks. We use these study global flow reduction induced removal single edge. analytically show that c...