the mean age of ftd onset is much younger than that of alzheimers disease. behavioral disturbances occur in early stages of ftd, and social dysfunction and personality deterioration may ensue. for this reason, it may be misdiagnosed with other psychiatric disorders. therefore, more careful observation and concern is required for proper diagnosis. our report is about a patient who was misdiagnos...

Cognitive decline most commonly associated with Alzheimer’s dementia can also result from other conditions including cerebral ischemia or brain trauma. One quarter of people over the age of 65 are estimated to suffer some form of cognitive impairment underscoring the need for effective classes of cognitive-enhancing agents. In this mini-review we highlight recent work from our laboratory on the...

The transdermal therapeutic systems (TTS) usually achieve constant plasma concentration for an extended period of time. This is because a sufficient drug stored in the device can keep the constant concentration on the surface of the stratum corneum during the system application. When the drug molecules are not enough to provide the constant surface concentration, the rate of drug penetration de...

This book is divided into four main sections. The first section describes noninvasive measures of cerebral aging, including structural (e.g., volumetric MRI), chemical (e.g., dopamine PET), electrophysiological (e.g., ERPs), and hemodynamic (e.g., fMRI), and discusses how they can be linked to behavioral measures of cognitive aging. The second section reviews evidence for the effects of aging o...

This book is divided into four main sections. The first section describes noninvasive measures of cerebral aging, including structural (e.g., volumetric MRI), chemical (e.g., dopamine PET), electrophysiological (e.g., ERPs), and hemodynamic (e.g., fMRI), and discusses how they can be linked to behavioral measures of cognitive aging. The second section reviews evidence for the effects of aging o...