Tracy K. Gosselin, RN, MSN, AOCN®, is the administrative director in the Department of Radiation Oncology at Duke University Medical Center in Durham, NC. Beatrice Mautner, RN, MSN, OCN®, is a clinical practice coordinator for Valley Radiotherapy Associates Medical Group, Inc., in Chatsworth, CA. (Mention of specific products and opinions related to those products do not indicate or imply endor...

In the title complex, [Mn(C(11)H(10)N(3)O(2))(2)]·3H(2)O, the Mn(II) atom is coordinated by four N atoms and two O atoms in a distorted octa-hedral geometry. The mol-ecules are linked together via hydrogen bonds involving the water molecules. One of these is disordered equally over two positions.

Despite reports of amifostine possibly protecting nephrotoxicity from cisplatin, it has not been recommended by any guidelines committees or routinely prescribed in clinical practice over the past decade. In this article, we review literature and regarding use oncology for protection against adverse effects certain chemotherapeutic agents, particular as a nephro-protectant patients receiving ci...

The purpose of the review is to briefly list widely used 43 drugs that can be as readily available non-toxic radioprotectors and radiomitigators in GDR relevant situations. Caffeine, acetylcysteine, ceruloplasmin, ibuprofen, acetylsalicylic acid, carnosine, cyclosporine, metformin, cholecalciferol, amifostine, artemisinin, theaflavin, succinic chlorophyllin, diltiazem, ferulic glutathione, glyc...

Abstract PURPOSE To evaluate the incidence and risk factors for hearing loss (HL) among children with medulloblastoma treated proton irradiation cisplatin. METHODS We identified ≥3 years of age at Texas Children’s Hospital between 2007-2022. Audiograms were graded using International Society Pediatric Oncology-Boston scale (SIOP-Boston). Time to grade HL was evaluated Kaplan-Meier multivariable...

BACKGROUND Hemorrhagic cystitis (HC) is a dose limiting side effect of cyclophosphamide (CYP). AIM In this study, we aimed to investigate the role of amifostine in the protection of CYP-induced HC and compare its efficacy with mesna. SETTING AND DESIGN This animal study was conducted in the Experimental Animals Breeding and Research Center of the Medical Faculty of Uludag University. MATE...

The Ni(II) atom in the title compound, [Ni(C(8)H(5)NO(4))(C(12)H(8)N(2))(H(2)O)(3)]·3H(2)O, is six-coordinated in an NiN(3)O(3) octa-hedral geometry. The triply water-coordinated Ni(II) atom is chelated by the phenantroline ligand and is additionally coordinated by the amino group of the 5-amino-isophtalate anion. The anion, the coordinated and the uncoordinated water mol-ecules inter-act throu...

Introduction: Radiation therapy is a well-established adjunct to surgical excision for soft tissue sarcomas and an alternative to surgery for Ewing's sarcoma of bone in pediatric patients. Radiation negatively impacts the growth plate in a growing child, leading to long-term complications. Radioprotectant drugs that protect healthy cells and tissues from the negative effects of radiation may be...