W E HAVE HAD a keen interest in the monoamine oxidase inhibitors (MAOinhibitors) from the time that Cesarman' first reported their benefits in the prophylaxis of angina pectoris. Together with two of my associates, Dr. Robert W. Oblath and Dr. Willard J. Zinn, I have used four of the available MAO-inhibitors-iproniazid, isocarboxazid, beta-phenylisopropylhydrazine, and pivalylbenzhydrazine-in t...

In the title compound, C(12)H(12)N(2)O, the dihedral angle between the planes of the pyridine and phenyl rings plane is 35.94 (12)°. In the crystal structure, centrosymmetrically related mol-ecules are linked by a pair of N-H⋯N hydrogen bonds, forming a dimer with an R(2) (2)(8) ring motif. In addition, there is an intra-molecular N-H⋯O inter-action.

In the title mol-ecule, C6H8N2, the endocyclic angles are in the range 118.43 (9)-122.65 (10)°. The mol-ecular skeleton is planar (r.m.s. deviation = 0.007 Å). One of the two amino H atoms is involved in an N-H⋯N hydrogen bond, forming an inversion dimer, while the other amino H atom participates in N-H⋯π inter-actions between the dimers, forming layers parallel to (100).

W E HAVE HAD a keen interest in the monoamine oxidase inhibitors (MAOinhibitors) from the time that Cesarman' first reported their benefits in the prophylaxis of angina pectoris. Together with two of my associates, Dr. Robert W. Oblath and Dr. Willard J. Zinn, I have used four of the available MAO-inhibitors-iproniazid, isocarboxazid, beta-phenylisopropylhydrazine, and pivalylbenzhydrazine-in t...

for the advantage of the reader how personality and timeliness of ideas have been major forces in the growth of our understanding of the "Wisdom of the Body." Especially to be recommended to students interested in tracing the background of modern concepts in neurophysiology are the essays by Professor Horace W. Magoun on "The development of ideas relating the mind with the brain," and Professor...

The title compound, C(7)H(10)N(2)O, crystallizes with two independent mol-ecules in the asymmetric unit. The bond lengths and angles in the mol-ecules are within normal ranges. The crystal structure is stabilized by inter-molecular N-H⋯N hydrogen bonds, linking the two independent mol-ecules into hydrogen-bonded dimers.

Polymer composition and morphology can affect the way polymers interact with biomolecules, cell membranes, and intracellular components. Herein, diblock, triblock, and statistical polymers that varied in charge center type (primary and/or tertiary amines) were synthesized to elucidate the role of polymer composition on plasmid DNA complexation, delivery, and cellular toxicity of the resultant p...