changes in extra and intracellular neurotransmitter amino acids concentration in the early stage of acute cerebral ischemia have been reported. in this the study, serum level of gamma aminobutyric acid (gaba) and l-arginine in acute ischemic stroke patients was assessed. 60 patients with acute ischemic stroke and sixthy healthy volunteers as a control group were assessed. serum gaba was measure...

although many studies have highlighted the role of gamma-aminobutyric acid (gaba) in the pathophysiology of psychosis, there is no drug-induced animal model in which gaba is manipulated. in this article we propose a hypothetical animal model for psychosis based on the silencing gabaergic system.  the presentation also suggest pre-pulse inhibition test as a preferred approach towards proving thi...

Accumulation of γ -aminobutyric acid (GABA) is associated with stress factors in plant systems. The objective of the current study was to compare GABA concentration in wheat plants under chilling stress. After 48 h treatments of seedlings under chilling stress combined stresses with and without GABA, morphological and biochemical assays were conducted. It was observed that the inhibition of see...

In this paper it has been shown that deterioration of the brain cortex capillary system and negative dynamics of cerebral tissue morphology occur under conditions of hypo kinesia. Simultaneously, gamma-aminobutyric acid (GABA) and piracetam have been shown to favor the development of vasodilation and prevent further worsening of the cerebral blood supply. During the experiment, it was also ...

Gamma-aminobutyric acid (GABA) is a non-protein amino that widely present in organisms. In particular, lactic bacteria (LAB) stand out this regard. The biosynthesis of GABA microorganisms mainly regulated by pH, which usually has the most pronounced effect on fermentation process. Also, production, affects media composition, time, and temperature. important positive functions human health. it k...

in this paper it has been shown that deterioration of the brain cortex capillary system and negative dynamics of cerebral tissue morphology occur under conditions of hypo kinesia. simultaneously, gamma-aminobutyric acid (gaba) and piracetam have been shown to favor the development of vasodilation and prevent further worsening of the cerebral blood supply. during the experiment, it was also esta...

glutamate decarboxylase enzyme produces γ-aminobutyric acid (gaba) in a non-reversible decarboxylation reaction of glutamate. gaba is a major inhibitory neurotransmitter of the brain and it is also present at high concentration in other organs such as pancreatic islets. gaba has effects on blood pressure, diabetes, inflammation, sleeplessness and depression. some bacteria such as lactobacillus ...

Gamma-aminobutyric acid (GABA) is a non-proteinogenic amino acid, which functions as neurotransmitter in the central nervous system. GABA has been shown to have several positive effects on human health, including reducing anxiety and promoting relaxation. In this study, various fermented fish products were screened for their ability produce GABA. A total of 35 lactic producing strains isolated ...

Fresh peaches are highly perishable and they deteriorate quickly during low temperature storage which results in losses in nutritional quality. To prevent these adverse effects, peach fruits were treated by dipping with γ-aminobutyric acid (GABA; 2, 4 and 6 mM) immediately after harvest and then stored at 1 °C for 7, 14, 21, and 28 days. Peach fruits treated with GABA exhibited higher flesh fir...

Objective(s) Diabetes related dysfunction of resistance vessels is associated with vascular occlusive diseases. Vasorelaxant agents may have a role in control of diabetic cardiovascular complications. Gamma aminobutyric acid (GABA) has demonstrated to cause vasorelaxation. The present study was designed to determine i) the vasorelaxatory effect of GABA on diabetic vessels and ii) the role of e...