نتایج جستجو برای: ampC

تعداد نتایج: 1706  

Journal: :Journal of clinical microbiology 2011
S Peter-Getzlaff S Polsfuss M Poledica M Hombach J Giger E C Böttger R Zbinden G V Bloemberg

Two mechanisms account for AmpC activity in Escherichia coli, namely, mutations in the ampC promoter and attenuator regions resulting in ampC overexpression and acquisition of plasmid-carried ampC genes. In this study, we analyzed 51 clinical E. coli isolates with reduced susceptibility to amoxicillin-clavulanic acid, piperacillin-tazobactam, or extended-spectrum cephalosporins for the presence...

Background & Objective: The production of plasmid-mediated AmpC beta-lactamases (PMABLs) among urinary Klebsiella pneumoniae isolates causes a severe problem to the successful treatment of urinary tract infections (UTIs). This study was designed to evaluate antimicrobial resistance, the presence of AmpC beta-lactamase genes, and the genetic relatedness among K. pneumoniae strains separated from...

2014
Akbar Mirsalehian Davood Kalantar-Neyestanaki Keramat Nourijelyani Kheirollah Asadollahi Morovat Taherikalani Mohammad Emaneini Fereshteh Jabalameli

BACKGROUND AND OBJECTIVES Pseudomonas aeruginosa is responsible for devastating nosocomial infections among severely burn patients. Class C of cephalosporinase (AmpC-β-lactamases) is important cause of multiple β-lactam resistance in P. aeruginosa. The aim of this study was to detect the AmpC-β-lactamases producing isolates among carbapenem resistant P. aeruginosa isolated from burn patient. ...

Journal: :The Journal of antimicrobial chemotherapy 2010
Rikke Lind Jørgensen Jesper Boye Nielsen Alice Friis-Møller Hans Fjeldsøe-Nielsen Kristian Schønning

OBJECTIVES To establish the prevalence of the AmpC beta-lactamase phenotype in clinical isolates of Escherichia coli and characterize the genetic resistance mechanisms causing the observed phenotype. METHODS Clinical E. coli (n = 74) with reduced susceptibility to third-generation cephalosporins and resistance to cefoxitin were collected from the Department of Clinical Microbiology at Hvidovr...

Journal: :Journal of clinical microbiology 2011
Silke Polsfuss Guido V Bloemberg Jacqueline Giger Vera Meyer Erik C Böttger Michael Hombach

In this prospective study all Enterobacteriaceae isolates (n = 2,129) recovered in the clinical microbiology laboratory during October 2009 to April 2010 were analyzed for AmpC production. Clinical and Laboratory Standards Institute (CLSI) cefoxitin and cefotetan susceptibility breakpoints and CLSI critical ESBL diameters were used to screen for potential AmpC producers. In total, 305 isolates ...

2012
Varsha Gupta Karthikeyan Kumarasamy Neelam Gulati Ritu Garg Padma Krishnan Jagdish Chander

BACKGROUND & OBJECTIVES AmpC β-lactamases are clinically significant since these confer resistance to cephalosporins in the oxyimino group, 7-α methoxycephalosporins and are not affected by available β-lactamase inhibitors. In this study we looked for both extended spectrum β-lactamases (ESBL) and AmpC β-lactamases in Klebsiella pneumoniae clinical isolates. METHODS One hundred consecutive, n...

2016
Fatin Izzati Mohd Khari Rina Karunakaran Roshalina Rosli Sun Tee Tay

OBJECTIVES The objective of this study was to determine the occurrence of chromosomal and plasmid-mediated β-lactamases (AmpC) genes in a collection of Malaysian isolates of Enterobacter species. Several phenotypic tests for detection of AmpC production of Enterobacter spp. were evaluated and the agreements between tests were determined. METHODS Antimicrobial susceptibility profiles for 117 E...

Journal: :iranian journal of microbiology 0
akbar mirsalehian department of microbiology, school of medicine, tehran university of medical sciences. tehran, iran. davood kalantar-neyestanaki department of microbiology, school of medicine, tehran university of medical sciences. tehran, iran. keramat nourijelyani department of epidemiology and biostatistics, school of public health, tehran university of medical sciences, tehran, iran. kheirollah asadollahi clinical microbiology research center, ilam university of medical sciences, ilam, iran. morovat taherikalani clinical microbiology research center, ilam university of medical sciences, ilam, iran. mohammad emaneini department of microbiology, school of medicine, tehran university of medical sciences. tehran, iran.

background  and  objectives: pseudomonas  aeruginosa is responsible for devastating nosocomial infections among severely burn patients. class c of cephalosporinase (ampc-β-lactamases) is important cause of multiple β-lactam resistance in p. aeruginosa . the aim of this study was to detect the ampc-β-lactamases producing isolates among carbapenem resistant p.  aeruginosa isolated from burn patie...

2010
R., Mohamudha Parveen B.N. Harish S.C. Parija

AmpC β-lactamases are cephalosporinases that hydrolyze cephamycins as well as other extended-spectrum cephalosporins and are poorly inhibited by clavulanic acid. Although reported with increasing frequency, the true rate of occurrence of AmpC β-lactamases in different organisms, including members of Enterobacteriaceae, remains unknown. The present study was designed to determine the occurrence ...

Journal: :The Indian journal of medical research 2003
A Subha V Renuka Devi S Ananthan

BACKGROUND & OBJECTIVES AmpC beta-lactamases are Group I cephalosporinases that confer resistance to a wide variety of beta-lactam drugs. Plasmid mediated AmpC beta-lactamases has been discovered most frequently in isolates of Klebsiella pneumoniae, K. oxytoca, Salmonella, Proteus mirabilis and Escherichia coli. The present study was undertaken to study the occurrence of multidrug resistant and...

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