in traditional medicine,some plants have been used as analysics.the aim of this investigation was to evaluate the analgesic effect of two plants,piper nigrum and Zingiber officinale that are used  traditionally to relieve headache,rheumatic arthritis,and toothache.for this purpose the methanolic extract of zingiber and piper nigrum,in different doses,were injected intraperitonealy to mice and t...

conclusions the ops is a good stand-alone pain score and is better than the nrs for defining mild and moderate pain. it may even be used to supplement nrs when it is indicative of mild or moderate pain. patient and methods a total of 1021 paired readings of the ops and nrs of 93 patients who underwent laparotomy and used patient-controlled analgesia were evaluated. acute pain service (aps) pers...

The report in this issue by Wood et aL I chronicles the development of a paediatric epidural analgesia programme at Alberta Children's Hospital. In these authors' experience, epidural analgesia was associated with good analgesia and safety, though with a considerable incidence of side effects and technical difficulties. Readers should not be put off by the quoted incidence of "complications"; m...

BACKGROUND Opioid-based postsurgical analgesia exposes patients undergoing laparoscopic colectomy to elevated risk for gastrointestinal motility problems and other opioid-related adverse events (ORAEs). The purpose of our research was to investigate postsurgical outcomes, including opioid consumption, hospital length of stay, and ORAE risk associated with a multimodal analgesia regimen, employi...

Although most randomized clinical trials conclude that the addition of continuous peripheral nerve blockade (CPNB) decreases postoperative pain and opioidrelated side effects when compared with opioids, studies have included relatively small numbers of patients and the majority failed to show statistical significance during all time periods for reduced pain or side effects. We identified studie...

Objective: To evaluate and compare the characteristics of spinal block, its postoperative analgesic effects, using intrathecal inj. Bupivacaine 0.5% and its combination with nalbuphine or buprenorphine in patients undergoing lower abdominal surgery. Methods: Sixty patients aged 30-60years scheduled for elective lower abdominal surgeries randomly received hyperbaric bupivacaine 0.5% 2.6 ml (grou...

The aim of the No Pain in Labour (NoPiL) study was to evaluate the stress and clinical outcome of infants vaginally born without maternal analgesia and after maternal epidural or systemic analgesia. We studied 120 healthy term infants, 41 in the no analgesia group, 38 in the epidural analgesia group, and 41 in the systemic analgesia group. Cortisol, beta-endorphin, oxidative stress markers (ie:...

Introduction: The starting point of this study was the considerably lower rate of epidural analgesia use among women of Turkish origin in Germany compared to non-immigrant women in the German Research Foundation (DFG)-funded study entitled "Perinatal Health and Migration Berlin". The study aimed to identify possible differences in the women's attitudes towards epidural analgesia. Methods: Explo...

INTRODUCTION Epidural analgesia provides excellent analgesia after major surgery but it is not without adverse effects. This retrospective study aims to evaluate the efficacy of analgesia and the problems commonly encountered postoperatively. MATERIALS AND METHODS Elective surgical patients who had epidural catheters inserted perioperatively intended for postoperative analgesia over a 1-year ...

SUMMARY The authors present three cases where catheters placed in the oblique sub-costal transversus abdominis plane provided prolonged analgesia after upper abdominal surgery. Patient 1 was admitted with severe sepsis following major hepatobiliary surgery. Bilateral catheters facilitated weaning from mechanical ventilation and provided adequate analgesia for 4 days. Patient 2 underwent emergen...