We report a 42-year-old male amateur body builder and user of anabolic androgenic steroids, who developed ARDS, acute kidney injury, and refractory supraventricular tachycardia. He required extracorporeal membrane oxygenation, continuous veno-venous hemodialysis, and catheter ablation. We believe that long-term anabolic androgenic steroid abuse predisposed the patient to multiple organ dysfunct...

BACKGROUND As oral contraceptives (OCs) suppress anti-Müllerian hormone (AMH), and hormonal contraceptives (HCs), likely, suppress functional ovarian reserve, this study was initiated to determine whether HC affect oocyte yields. METHODS We investigated in a retrospective cohort study 43 oocyte donors in 71 in vitro fertilization (IVF) cycles, evaluating anti-Müllerian hormone (AMH) and oocyt...

Estrogenic and androgenic activities of wastewater were determined during treatment in five wastewater treatment works (WWTWs) in the Untied Kingdom. With one exception, both estrogenic and androgenic activities decreased markedly as wastewater progressed through the plants; removal rates were generally 70% or higher, sometimes reaching 100%. Most of the reduction in activity occurred during se...

Background: The purpose of this study was to evaluate the effect of Ruta graveolens (RG) Aqueous Extract on in vitro fertilization (IVF) rate and embryo development. RG, commonly called sudab or rue, has been known as a medical plant since ancient times. Recently some medicinal properties were reported for RG such as: antioxidant, anti-inflammatory, anti-tumor, anti-androgenic, anti- conceptive...

Introduction: The use of anabolic androgenic steroids is particularly common in regular gyms and fitness centres participants. AAS are usually synthetic derivatives testosterone with effect. However, many people, including users, do not realize how side effects they can cause.The aim the study: study was to assess if people who regularly attend gym aware using by empirical research based on ano...

Background: Development of cloned bovine embryos. Materials and Methods: Oocytes collection,oocyte denudation, oocyte enucleation, nuclear transfer, electrofusion, reconstructed embryo activation, culture of reconstructed and IVF embryo,and treatment with SAH post fusion interval Treatment of reconstructed embryos with TSA for 12 hours after activation, preparation of somatic donor cells, donor...

Svensson, J. 2016. Progestagenic Aquatic Contaminants Act as Potent Androgens in Fish. Experimental Studies in Three-spined Stickleback and Zebrafish. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology 1379. 45 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-554-9587-9. The extensive use of pharmaceuticals and their poor removal by waste...

Cognitive abilities, such as verbal fluency and mental rotation, are most sensitive to changes in sex steroids but poorly studied in the context of hormonal contraceptive usage. Therefore, we investigated the performance of mental rotation and verbal fluency in young (21.5±1.8 years) healthy oral contraceptive (OC) users (23 women) and non-users (20 women) during the follicular, ovulatory and l...

There is presently considerable interest in endocrine disruption which is a new area of endocrinology concerned with chemicals that mimic hormones, in particular sex steroids. It has been hypothesised that exposure to such chemicals may be responsible for adverse effects in both humans and wildlife. Until now, chemicals that mimic oestrogens (so-called xenoestrogens) have been the main focus of...