Levonorgestrel (LNg) is known for its marked progestational/contraceptive activity. As shown in animal experiments, however, high doses of LNg are required to elicit an androgenic response; in contrast, considerably lower doses of LNg are required for antiovulatory (contraceptive) action. Thus, a large dose separation exists between androgenic and contraceptive activity. When LNg is combined wi...

background: anabolic-androgenic steroids are used at high doses by athletes for improving athletic ability, physical appearance and muscle mass. therefore, the abuse of these steroids has been significantly increased. many undesirable side effects of these steroids on the male reproductive function have been reported, however, little is known about their effects on sexual behavior and tissues o...

OBJECTIVE The authors investigated the use and perceived use of anabolic androgenic steroids (AAS) among nonathlete college students. PARTICIPANTS The authors surveyed a sample of 485 nonathlete college students at a major metropolitan university. METHODS They administered a survey on use and perceived use of AAS to the students. RESULTS Forty-two participants (9%) reported using AAS (37 ...

appendix, over-all this volume deserves nothing but praise. It is an absolute "must" for anyone who enters this complicated field. Moreover, the organization of the book is such that the casual reader seeking an isolated bit of information will be as well served as he who sits and studies it intensively. The book is highly recommended to anyone whose interests include an understanding of the bi...

BACKGROUND Alcohol is one of the most common causes of liver disease in the Western World today. Randomised clinical trials have examined the effects of anabolic-androgenic steroids for alcoholic liver disease. OBJECTIVES The objectives were to assess the beneficial and harmful effects of anabolic-androgenic steroids for patients with alcoholic liver disease based on the results of randomised...

Anabolic androgenic steroids (AAS) and testosterone are the most frequently detected prohibited doping agents in sport. Professional competitors have been taking them since the fifties of the 20th century, they are used at present mainly by sport amateurs. Anabolic Androgenic Steroids are very often used in combination with other doping agents (erythropoietin, growth hormone, thyroxin). Apart f...

Trans-anethole was studied for antifertility activity in rats at dose levels of 50 mg, 70 mg and 80 mg/kg po. Dose-dependent activity was observed, a 100% anti-implantation activity being achieved at 80 mg/kg, po. The compound showed a significant estrogenic activity and did not possess anti-estrogenic, progestational, anti-progestational, androgenic or anti-androgenic activities. In an earlier...

introduction anabolic-androgenic steroids (aas), a synthetic derivate of testosterone, have become a popular drug among athletes and bodybuilders to enhance muscle mass and improve the athletic performance. many pathological effects such as hepatic and endocrine dysfunction, behavioural changes and cardiovascular complications have been reported. case report within these ast ones, we find an in...

A better understanding of the different phenotypes and of their endocrine and metabolic characteristics permits investigators to distinguish three main androgen excess disorders: classic polycystic ovary syndrome (PCOS), mild ovulatory PCOS, and idiopathic hyperandrogenism. These androgenic phenotypes differ more for the severity of the endocrine and metabolic alteration than for the etiopathog...