In India, mutations in Cytochrome P450 (CYP1B1) are a predominant cause of not only primary congenital glaucoma (PCG) but also involved in primary open angle glaucoma (POAG) and juvenile onset glaucoma (JOAG). After ethical clearance, 100 POAG patients, 30 primary angle closure glaucoma (PACG) patients and 130 ethnically matched controls were recruited in this study. Genomic DNA was is...

there are reports from different countries that some types of glaucoma are associated with blood groups. this cross-sectional study was performed on 400 glaucomatous patients [100 patients in each group of primary open angle glaucoma (poag), chronic angle closure glaucoma (cacg), pseudoexfoliative glaucoma (pexg) and primary congenital glaucoma (pcg)] and 400 blood donors as control group to as...

background: glaucomatous neuropathy is a type of cell death due to apoptosis. the p53 gene is one of the regulatory genes of apoptosis. recently, the association between the p53 gene encoding for proline at codon 72 and primary open-angle glaucoma (poag) has been studied in some ethnic groups. this study is the first association analysis of poag and p53 codon 72 polymorphism in iranian patients...

Aim: To study the prevalence of Glaucoma and its sub types in North costal Andhra Pradesh South India. Results: Among total number 2,98,971 General ophthalmic OPD individuals, 4836 individuals referred to clinic on suspicion glaucoma 4320 patients are confirmed have after doing relevant investigations. 1884 primary open angle (POAG), 1057 Primary Angle closure disease (PACD), 702 suspect or at ...

PURPOSE To determine the prevalence of glaucoma and risk factors for primary open-angle glaucoma in a rural population of southern India. DESIGN A population-based cross-sectional study. PARTICIPANTS A total of 5150 subjects aged 40 years and older from 50 clusters representative of three southern districts of Tamil Nadu in southern India. METHODS All participants had a comprehensive eye ...

Background: Glaucomatous neuropathy is a type of cell death due to apoptosis. The p53 gene is one of the regulatory genes of apoptosis. Recently, the association between the p53 gene encoding for proline at codon 72 and primary open-angle glaucoma (POAG) has been studied in some ethnic groups. This study is the first association analysis of POAG and p53 codon 72 polymorphism in Iranian patients...

objective: to compare the frequency of helicobacter pylori (h. pylori) infection in subjects with primary open angle glaucoma (poag) vs controls. methods: in a case-control study, 44 patients with primary open angle glaucoma and 79 patients with senile cataract (control group) were investigated for serum level of anti-h. pylori antibody using the enzyme-linked immunosorbant assay (elisa) method...

Purpose The purpose of this study was to comparatively evaluate angle dysgenesis in vivo, among congenital, juvenile, and adult-onset open angle glaucoma patients. Methods A cross-sectional evaluation of 96 glaucoma patients, 22 children with primary congenital glaucoma (PCG) old enough to cooperate for optical coherence tomography (OCT), 34 juvenile-onset open angle glaucoma (JOAG) patients,...

OBJECTIVES To investigate the prevalence of myocilin (MYOC) mutations in Italian families with glaucoma and to determine the relationship of these mutations to primary open-angle glaucoma (POAG), juvenile open-angle glaucoma (JOAG), and pigmentary dispersion glaucoma. METHODS Twenty-six patients with POAG were selected based on a positive family history of glaucoma. All patients and 210 relat...

The literature analysis confirms the interrelationship of thyroid gland pathology and glaucoma. Patients with diffusetoxic goiter (DTG) endemic have an especially high risk developing glaucoma, while those autoimmune thyroiditis face a moderate risk. prevalence primary open angle glaucoma (POAG) in patients over 40 endocrine ophthalmopathy is reliably associated male gender duration disease lon...