Keywords: Modeling. Flow in porous media. Flow in aquifers. Transport in porous media. Saturated flow. Darcy's law. Dispersion. Variable density flow and transport.

1 Istituto per l’Endocrinologia e l’Oncologia Sperimentale (IEOS), CNR, 80131 Naples, Italy 2Santiago University Clinical Hospital, Instituto de Investigación Sanitaria de Santiago (IDIS), 15706 Santiago de Compostela, Spain 3Human Cancer Genetics Program/CCC, The Ohio State University, Columbus, OH 43210, USA 4Department of Clinical and Molecular Medicine, Sapienza University of Rome, 00100 Ro...

In this eighteenth (2016) Annual Review Issue of The Journal of Pathology, we present a collection of 19 invited review articles that cover different aspects of cellular and animal models of disease. These include genetically-engineered models, chemically-induced models, naturally-occurring models, and combinations thereof, with the focus on recent methodological and conceptual developments acr...

As the main theme of this special issue, CRP not only is an inflammatory marker but also has diverse biological functions associated with different diseases. To investigate CRP's physiologies and their relationship with human pathological significance, it is essential to use appropriate animal models for translational research. The most popular models for the study of CRP are transgenic mice. H...

P reterm birth results in considerable disability, yet several reports suggest recovery from injury in developing brain. Developmental compensatory mechanisms may promote neural and functional plasticity, and numerous experimental studies have documented the brain’s ability to engage in regenerative mechanisms to potentially replace injured cells. We review available evidence for recovery from ...