objective(s): adipose derived stem cells (adscs) can be engineered to express bone specific markers. the aim of this study is to evaluate repairing tibia in animal model with differentiated osteoblasts from autologous adscs in alginate scaffold. materials and methods: in this study, 6 canine’s adscs were encapsulated in alginate and differentiated into osteoblasts. alkaline phosphatase assay (a...

objective(s) seed of cucumis sativus linn. is one of the herbal remedies has been traditionally used for diabetes mellitus treatment. we studied the effect of hydroalcoholic and buthanolic extract obtained from c. sativus seeds in a model of streptozotocin (stz)-induced diabetic (type i) rats. materials and methods normal and diabetic male wistar rats (stz, 60 mg/kg, intraperitoneal) were treat...

abstract unbalance using of chemical fertilizers cause decline the soil quality and fertility, environmental pollution and specially soil and water resources pollution. the use of animal manure is a replacement to chemical fertilizers. therefore, recognizing of demographic, technical-extensional and agronomic affect on farmer's decision making process to use of animal manure will have important...

objective: the aim of this study was to determine the protective effects of coriandrum sativum on acetic acid-inducedcolitis in rats. c. sativum (coriander) has long been used in iranian traditional medicine and its use as an anti-inflammatory agent is still common in some herbal formulations.  materials and methods: colitis was induced by intra-rectal administration of 2ml acetic acid 4% in fa...

the main aim of this research was to estimate the genetic and phenotypic parameters for productive and reproductive traits of esfahan native chickens. traits included body weights at hatch (bw1), 8 weeks of age (bw8), 12 weeks of age (bw12), and at sexual maturity (wsm)], age at sex maturity (asm), egg number (en), average egg weight (aew) in the first 12 weeks of production, and egg production...

(co) variance components and genetic parameters for growth traits in arman sheep were estimated, using data collected during an 11-year period (1999-2010), by applying the restricted maximum likelihood (reml) procedure under univariate and bivariate animal models. the studied traits were body weight of lamb at birth (bw), body weight at 3 months of age as weaning weight (ww), body weight at 6 m...

introduction: alzheimer’s disease (ad) is one of the most common neurodegenerative disorders, which has much benefited from animal models to find the basics of its pathophysiology. in our previous work (haghani, shabani, javan, motamedi, & janahmadi, 2012), a non-transgenic rat model of ad was used in electrophysiological studies. however, we did not investigate the histological aspects in the ...

this study was designed to develop a modified tbi weight drop model for induction of focal mild cerebral injury. a stereotaxic coupled weight drop device was designed. principle arm of device carries up to 500g weights which their force was conveyed to animal skull through a thin nail like metal tip. to determine the optimal configuration of the device to induce mild tbi, six different trials w...

objective: leishmaniasis is one of the six most common parasitic infections in tropical regions. there are different therapeutic modalities. however therapeutic resistance is developed and resulted in numerous problems. so evaluation of other therapeutic modalities is performed extensively. we compared the therapeutic response of cutaneous leishmaniasis with glucantime and garlic extract and it...

we aimed to evaluate the potential of growing rats as a model of osteoporosis induced by short term hypercholesterolemia. twelve growing female sprague-dawley rats were randomly allocated into two groups. control rats received standard diet while rats in group 2 were fed with diet contained 20% sunflower oil, 2% cholesterol and 0.5% cholic acid for 2 weeks and then a diet contained 10% sunflowe...