BACKGROUND AND THE PURPOSE OF THE STUDY Artemisinin is one of the most effective medicine against malaria, which is produced naturally by Artemisia annua in low yield. It is produced in a metabolic pathway, in which several genes and gene products are involved. One of the key genes in this pathway is am1, which encodes amorpha-4, 11-diene synthase (ADS), a key enzyme in artemisinin biosynthesis...

Front Cover/Cover Picture. Artemisia annua L. is an annual herb of Asteraceae family, one the famous traditional Chinese medicines, commonly known as “Qing Hao”. However, in Chongming District Shanghai, it called “Ku Cao” and has been used for women's post-natal rehabilitation a long time. In this study, five new monoterpene glycosides (1–5) two sesquiterpenoid (6 7) were isolated from water ex...

Abstract The leaves of different species the genus Artemisia show considerable inner and external structural diversity. This paper presents a comparative study micromorphological features leaf surface for seven from regions Ukraine: A. absinthium L., annua dracunculus marschalliana Spreng., vulgaris argyi H.Lév. & Vaniot, verlotiorum Lamotte. vegetative organs these plants have potentially ...

Humans around the globe probably discovered natural remedies against disease and cancer by trial and error over the millennia. Biomolecular archaeological analyses of ancient organics, especially plants dissolved or decocted as fermented beverages, have begun to reveal the preliterate histories of traditional pharmacopeias, which often date back thousands of years earlier than ancient textual, ...

In parts of Africa and Asia, self-medication with a hot water infusion of Artemisia annua (Artemisia tea) is a common practice for a number of ailments including malaria and cancer. In our earlier work, such an extract showed better potency than artemisinin alone against both chloroquine-sensitive and -resistant parasites. In this study, in vitro tests of the infusion in MCF7 cells showed high ...

the chemical composition of the essential oils of flower at the pre-flowering, full-flowering and post-flowering stage of a. annua was analyzed by gc and gc/ms and sixty-two components were identified. the main compounds in the pre-flowering oil were β-myrcene (37.71%), 1, 8-cineole (16.11%) and camphor (14.97%). the full-flowering oil contained predominantly caryophyllene (19.4%), germacrene d...