R(-)-deprenyl has been shown to rescue axotomized immature facial motoneurons with an efficacy comparable to that of the neurotrophic factors CNTF and BDNF (Salo and Tatton, J Neurosci Res 31:394-400, 1992; Ansari et al., J Neurosci 13:4042-4053, 1993). Recent work has suggested that some of the actions of (-)-deprenyl may be mediated through reactive astrocytes (Biagini et al., NeuroReport 4:9...

This paper investigates the problem of dynamic survivable lightpath provisioning against single-link failure in optical mesh networks employingwavelength-divisionmultiplexing (WDM).We focus on the special problem of provisioning lightpath requests according to their differentiated protection-switching time, since lightpath may have different protection-switching time requirements. We assume tha...

the logical next step. And yet achieving this goal poses many challenges given the relatively small Canadian research capacity in this area. El Ansari et al. 11 suggested that, to accelerate research activity, research consortiums deserve attention by funding bodies. We agree, and we propose the establishment of a consortium to advance needed work in cancer survivorship in Canada. A research co...

M any chronic conditions, such as diabetes or asthma, can be successfully managed in the community. Appropriate screening, ongoing monitoring, prescribing of medications, providing patient education and other supportive measures that help keep these conditions under control are provided in primary healthcare settings. However, sometimes people with such conditions require hospitalization. Altho...

Background: Sirtuin1 (Sirt1) is a member of highly conserved proteins and has been implicated as a tumor promoter as well as a tumor suppressor. One of the mechanisms involves deacetylation of retinoblastoma protein, thereby inhibiting the tumor suppressor function. No study has been reported on the expression of Sirt1 in retinoblastoma. Methods: We assessed the expression of Sirt1 in sections ...

Objective: HYBID (Hyaluronan Binding Protein Involved in HA Depolymerization, KIAA1199) is a hyaluronan (HA) binding protein, which involves in depolymerization of HA. It is reported that HYBID mRNA is expressed in the lung, heart, skin and brain in murine and human. However, the role of HYBID in the brain remains unclear. In this study, we have made HYBID KO mice and evaluated its function in ...

Daucus carota Linn. (Family: Umbeliferae) is an annual or biennial herb, whose roots are eaten raw and also cooked in many parts of the world. It is cultivated extensively through out the world including India. The root of the plant is used as a diuretic and inotropic (Chaterjee and Prakesh, 1995). The volatile oil from the seeds are reported to possess analgesic and anti-inflammatory activity ...